Abstract: [Abstract] Objective: To analysis the cause of hospitalization and related risk factor in patients with maintenance hemodialysis. Method: 99 hemodialysis patients were enrolled. Age, dialysis age, blood pressure, hemoglobin, blood glucose, serum creatinin, serum potassium, serum calcium, serum phosphorus, albumin, iPTH and KT/V were compared in hospitalization and non-hospitalization groups. The main cause and related risk factor for hospitalization were reviewed. Result: 59 out of 99 patients were hospitalized and they have 106 hospitalizations in observed period. Average hospitalization was 1.07±1.22 per patient and hospitalized days were 28.27±24.73 days per hospitalized patients. The main causes of hospitalization were cardiovascular disease, vascular access stenosis and pulmonary infection. Compare with non-hospitalization group, age of patient hospitalization group was older and the levels of albumin and serum creatinin were lower than those in MHD patients. （66.6±12.62 vs.56.63±13.16 years,p=0.00; 804.05±226.01 vs.954.80±226.35μmol/L，p=0.03; 33.13±4.16 vs.37.30±3.33 g/L，p=0.000）. Stepwise multivariate regression analysis showed hypoablbuminia and short dialysis age were risk factors to influence the hospitalization patients undergoing maintenance hemodialysis. Stepwise multivariate regression analysis showed hypoablbuminia and short dialysis age were risk factors to influence the hospitalization in patients undergoing maintenance hemodialysis. Conclusion: Cardiovascular disease, vascular access stenosis and pulmonary infection were the important causes for hospitalization in hemodialysis patient. Cardiovascular disease was the leading cause of hospitalization in patients with maintenance hemodialysis.

Key words: Hemodialysis, Hospitalization, Risk factor