【Abstract】Objective To analyze the long-term patency in hemodialysis patients with lower extremity arteriovenous grafts (AVG). Method This was a retrospective analysis including 19 lower extremity AVGs constructed during January 2015 to October 2017. Their primary, assisted primary and secondary patency rates were calculated. The events leading to patency failure were analyzed. The stenosis sites were described. Results A total of 19 patients were enrolled in this study. At the 6th month, 12th month and 24th months, the primary patency rates were 79 %, 63 % and 31 % respectively, the assisted primary patency rates were 100 %, 95 % and 69 % respectively, and the secondary patency rates were all 100 %. Conclusion Lower extremity AVG had lower patency rate, but it still can be optional in patients with unusable upper extremity vein.