中国血液净化

中国血液净化 ›› 2019, Vol. 18 ›› Issue (04): 242-245.doi: 10.3969/j.issn.1671-4091.2019.04.008

• 临床研究 • 上一篇    下一篇

维持性血液透析患者中瘙痒症的现状调查研究

陈敢1,王丽妍2,傅君舟1,刘文虎2,吴雯婷3,谢志强4   

  1. 1广州市第一人民医院肾内科
    2首都医科大学附属北京友谊医院肾病内科
    3东丽国际贸易(中国)有限公司
    4北京大学第三医院皮肤科(陈敢、王丽妍为共同第一作者)
  • 收稿日期:2018-10-30 修回日期:2019-01-04 出版日期:2019-04-12 发布日期:2019-04-12
  • 通讯作者: 谢志强 xiezq@bjmu.edu.cn E-mail:xiezq66@163.com

Pruritus in maintenance hemodialysis patients

  • Received:2018-10-30 Revised:2019-01-04 Online:2019-04-12 Published:2019-04-12

PDF

1097

摘要： 【摘要】目的了解成年维持性血液透析患者中皮肤瘙痒的症状特征及治疗情况。方法以广州和北京患有瘙痒症的血液透析患者为对象，调查瘙痒的症状特征、治疗情况及影响因素。结果本研究共128 例有效病例数据纳入分析。在患有瘙痒症的血液透析患者中，中度以上瘙痒占49.22%。患者瘙痒部位多见于背部(75.78%)和下肢(57.81%)，并在夜间(73.44%)及冬天(62.50%)多发。46.88%的患者有明显抓痕，28.13%的患者表示因瘙痒感到焦虑。瘙痒程度随年龄增长而增强(t=2.577, P=0.011)。12.50%的患者接受针对瘙痒的治疗，治疗满意率为37.50%。结论血液透析患者瘙痒症会引起皮肤继发性损伤和自觉焦虑情绪，近半数患者瘙痒程度呈中度以上，且瘙痒程度与其年龄有关。但患者的瘙痒症治疗率非常低，且其治疗满意率也较低。

关键词: 瘙痒症, 皮肤瘙痒, 血液透析, 尿毒症

Abstract: 【Abstract】Objective To understand the symptom features and treatment condition of pruritus in maintenance hemodialysis (MHD) patients. Methods MHD patients with pruritus in Guangzhou and Beijing were recruited in this study. Symptoms, treatment situation and factors influencing pruritus severity were investigated. Results A total of 128 patients were enrolled in this study, and 49.22% of them had moderate to extreme pruritus. Pruritus was mainly occurred on back (75.78%) and lower limbs (57.81%), often occurring during night (73.44%) and in winter (62.50%); 46.88% of the patients were found to have scratches on skin; 28.13% of the patients were suffering from anxiety. The severity of pruritus increased with age (t=2.577, P=0.011); 12.50% of the patients receive treatment for pruritus, with the satisfaction rate of 37.50% to the treatment. Conclusions Uremic pruritus can cause skin damage and anxiety. Nearly half of the patients had moderate to extreme pruritus. The severity of pruritus was related to age. However, only a few patients received the treatment for pruritus and the satisfaction rate was quite low.

Key words: Pruritus, Itch, Hemodialysis, Uremia