腹膜透析相关腹膜炎抗生素疗程研究现状

doi:10.3969/j.issn.1671-4091.2021.09.002

中国血液净化 ›› 2021, Vol. 20 ›› Issue (09): 581-585.doi: 10.3969/j.issn.1671-4091.2021.09.002

• 专题与讲座·党为人民谋健康的100年 • 上一篇下一篇

腹膜透析相关腹膜炎抗生素疗程研究现状

李欣秋¹,杨志凯¹,董捷¹

1北京大学第一医院肾脏内科，北京大学肾脏疾病研究所，卫生部肾脏疾病重点实验室，
教育部慢性肾脏疾病预防与治疗重点实验室，中国医学科学院免疫介导肾病诊治创新单元

收稿日期:2021-05-20 修回日期:2021-06-10 出版日期:2021-09-20 发布日期:2021-09-12
通讯作者: 杨志凯 seapollar@126.com E-mail:seapollar@126.com

Current status of research about antibiotic courses of peritoneal dialysis associated peritonitis

1Department of Nephrology, Peking University First Hospital, Institute of Kidney Disease of Peking University, Key Laboratory of Kidney Disease of Ministry of Health, Key Laboratory of Prevention and Treatment of Chronic Kidney Disease of Ministry of Education, Research Units of Diagnosis and Treatment of ImmunEmediated Kidney Diseases, Chinese Academy of Medical Sciences, Beijing 100034, China

Received:2021-05-20 Revised:2021-06-10 Online:2021-09-20 Published:2021-09-12
Contact: Zhi-kai YANG E-mail:seapollar@126.com

摘要/Abstract

摘要： 【摘要】腹膜透析相关腹膜炎是腹膜透析常见的并发症，影响腹膜透析患者预后。合理的抗生素疗程既保证腹膜炎治疗有效率，又有助于减少细菌耐药率，降低医疗费用。本文回顾了关于腹膜透析相关腹膜炎抗生素疗程的研究，总结现有研究存在的问题，并提供建议，以期对后续研究的开展提供参考。

关键词: 腹膜透析相关腹膜炎, 抗生素疗程

Abstract: 【Abstract】Peritonitis is an important complication of peritoneal dialysis (PD), commonly affecting the prognosis of patients on peritoneal dialysis. The appropriate course of antibiotics is essential to the therapeutic effect, in terms of reducing manpower and expenditure, and drug resistance rate as well. We reviewed the literature on the antibacterial course of peritonitis associated with PD and summarized limitations with the existing evidence and provided relevant suggestions. Future researches are warranted to elucidate it.

Key words: Peritoneal dialysis associated peritonitis, Antibiotics course

中图分类号:

R453.2

李欣秋, 杨志凯, 董捷. 腹膜透析相关腹膜炎抗生素疗程研究现状[J]. 中国血液净化, 2021, 20(09): 581-585.

参考文献

[1]Mehrotra R, Devuyst O, Davies SJ, et al.The Current State of Peritoneal Dialysis[J].J Am Soc Nephrol, 2016, 27(11):3238-3252 [2]Wilkie M, Davies S.Insights on Peritoneal Dialysis in China[J].Perit Dial Int, 2018, 38(Suppl 2):S16-s18 [3]Hsieh YP, Chang CC, Wen YK, et al.Predictors of peritonitis and the impact of peritonitis on clinical outcomes of continuous ambulatory peritoneal dialysis patients in Taiwan--10 years' experience in a single center[J].Perit Dial Int, 2014, 34(1):85-94 [4]Miles R, Hawley CM, McDonald SP, et al.Predictors and outcomes of fungal peritonitis in peritoneal dialysis patients[J].Kidney Int, 2009, 76(6):622-628 [5]Davenport A.Peritonitis remains the major clinical complication of peritoneal dialysis: the London,UK,peritonitis audit 2002-2003[J].Perit Dial Int, 2009, 29(3):297-302 [6]Brown MC, Simpson K, Kerssens JJ, et al.Peritoneal dialysis-associated peritonitis rates and outcomes in a national cohort are not improving in the post-millennium (2000-2007)[J].Perit Dial Int, 2011, 31(6):639-650 [7]Boudville N, Kemp A, Clayton P, et al.Recent peritonitis associates with mortality among patients treated with peritoneal dialysis[J].J Am Soc Nephrol, 2012, 23(8):1398-1405 [8]Pérez Fontan M, Rodríguez-Carmona A, García-Naveiro R, et al.Peritonitis-related mortality in patients undergoing chronic peritoneal dialysis[J].Perit Dial Int, 2005, 25(3):274-284 [9]Capobianco A, Cottone L, Monno A, et al.The peritoneum: healing,immunity,and diseases[J].J Pathol, 2017, 243(2):137-147 [10]Htay H, Cho Y, Johnson DW.Longer antibiotic durations for treating peritoneal dialysis-associated peritonitis: helpful or harmful?[J].Clin Kidney J, 2021, 14(3):735-738 [11]Roubaud-Baudron C, Ruiz VE, Swan AM, Jr.Long-Term Effects of Early-Life Antibiotic Exposure on Resistance to Subsequent Bacterial Infection[J][J].mBio, 2019, 10(6):e02820-19 [12]Valour F, Karsenty J, Bouaziz A, et al.Antimicrobial-related severe adverse events during treatment of bone and joint infection due to methicillin-susceptible Staphylococcus aureus[J].Antimicrob Agents Chemother, 2014, 58(2):746-755 [13]Atkins D, Eccles M, Flottorp S, et al.Systems for grading the quality of evidence and the strength of recommendations I: critical appraisal of existing approaches The GRADE Working Group[J].BMC Health Serv Res, 2004, 4(1):38-38 [14]Szeto CC, Kwan BC, Chow KM, et al.Coagulase negative staphylococcal peritonitis in peritoneal dialysis patients: review of 232 consecutive cases[J].Clin J Am Soc Nephrol, 2008, 3(1):91-97 [15]Fahim M, Hawley CM, McDonald SP, et al.Coagulase-negative staphylococcal peritonitis in Australian peritoneal dialysis patients: predictors,treatment and outcomes in 936 cases[J].Nephrol Dial Transplant, 2010, 25(10):3386-3392 [16]Edey M, Hawley CM, McDonald SP, et al.Enterococcal peritonitis in Australian peritoneal dialysis patients: predictors,treatment and outcomes in 116 cases[J].Nephrol Dial Transplant, 2010, 25(4):1272-1278 [17]Yip T, Tse KC, Ng F, et al.Clinical course and outcomes of single-organism Enterococcus peritonitis in peritoneal dialysis patients[J].Perit Dial Int, 2011, 31(5):522-528 [18]Shukla A, Abreu Z, Bargman JM.Streptococcal PD peritonitis--a 10-year review of one centre's experience[J].Nephrol Dial Transplant, 2006, 21(12):3545-3549 [19]O' Shea S, Hawley CM, McDonald SP, et al.Streptococcal peritonitis in Australian peritoneal dialysis patients: predictors, treatment and outcomes in 287 cases[J]. [J].BMC Nephrol, 2009 , Jul 26(10):19-19 [20]Szeto CC, Chow KM, Chung KY, et al.The clinical course of peritoneal dialysis-related peritonitis caused by Corynebacterium species[J].Nephrol Dial Transplant, 2005, 20(12):2793-2796 [21]Barraclough K, Hawley CM, McDonald SP, et al.Corynebacterium peritonitis in Australian peritoneal dialysis patients: predictors,treatment and outcomes in 82 cases[J].Nephrol Dial Transplant, 2009, 24(12):3834-3839 [22]Htay H, Cho Y, Pascoe EM, et al.Outcomes of Corynebacterium Peritonitis: A Multicenter Registry Analysis[J].Perit Dial Int, 2017, 37(6):619-626 [23]Szeto CC, Chow KM, Kwan BC, et al.Staphylococcus aureus peritonitis complicates peritoneal dialysis: review of 245 consecutive cases[J].Clin J Am Soc Nephrol, 2007, 2(2):245-251 [24]Govindarajulu S, Hawley CM, McDonald SP, et al.Staphylococcus aureus peritonitis in Australian peritoneal dialysis patients: predictors,treatment,and outcomes in 503 cases[J].Perit Dial Int, 2010, 30(3):311-319 [25]Fahim M, Hawley CM, McDonald SP, et al.Culture-negative peritonitis in peritoneal dialysis patients in Australia: predictors,treatment,and outcomes in 435 cases[J].Am J Kidney Dis, 2010, 55(4):690-697 [26]Barraclough K, Hawley CM, McDonald SP, et al.Polymicrobial peritonitis in peritoneal dialysis patients in Australia: predictors,treatment,and outcomes[J].Am J Kidney Dis, 2010, 55(1):121-131 [27]Szeto CC, Chow KM, Leung CB, et al.Clinical course of peritonitis due to Pseudomonas species complicating peritoneal dialysis: a review of 104 cases[J].Kidney Int, 2001, 59(6):2309-2315 [28]Siva B, Hawley CM, McDonald SP, et al.Pseudomonas peritonitis in Australia: predictors,treatment,and outcomes in 191 cases[J].Clin J Am Soc Nephrol, 2009, 4(5):957-964 [29]Lui SL, Lo CY, Choy BY, et al.Optimal treatment and long-term outcome of tuberculous peritonitis complicating continuous ambulatory peritoneal dialysis[J].Am J Kidney Dis, 1996, 28(5):747-751 [30]Lui SL, Tang S, Li FK, et al.Tuberculosis infection in Chinese patients undergoing continuous ambulatory peritoneal dialysis[J].Am J Kidney Dis, 2001, 38(5):1055-1060 [31]Szeto C-C, Ng JK-C, Wing-Shing Fung W, et al.Extended antibiotic therapy for the prevention of relapsing and recurrent peritonitis in peritoneal dialysis patients: a randomized controlled trial[J].Clinical Kidney Journal, 2021, 14(3):991-997 [32]Piraino B, Bailie GR, Bernardini J, et al.Peritoneal dialysis-related infections recommendations: 2005 update[J].Perit Dial Int, 2005, 25(2):107-131 [33]Li PK, Szeto CC, Piraino B, et al.ISPD Peritonitis Recommendations: 2016 Update on Prevention and Treatment[J].Perit Dial Int, 2016, 36(5):481-508 [34]Rüger W, van Ittersum FJ, Comazzetto LF, et al.Similar peritonitis outcome in CAPD and APD patients with dialysis modality continuation during peritonitis[J].Perit Dial Int, 2011, 31(1):39-47 [35]Yang L, Gong N, Zhou H, et al.The pathogen spectrum and resistance in patients with peritoneal dialysis-associated peritonitis: A single-center, observational clinical study?[J]. [J].Clin Nephrol, 2019, 92(1):44-51 [36]Wong SS, Ho PL, Yuen KY.Evolution of antibiotic resistance mechanisms and their relevance to dialysis-related infections[J]. [J].Perit Dial Int, 2007, 27( Suppl 2):272-280

腹膜透析相关腹膜炎抗生素疗程研究现状

Current status of research about antibiotic courses of peritoneal dialysis associated peritonitis

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 0

编辑推荐

Metrics

本文评价