中国血液净化

中国血液净化 ›› 2024, Vol. 23 ›› Issue (04): 290-293.doi: 10.3969/j.issn.1671-4091.2024.04.011

• 综述 • 上一篇    下一篇

血液透析患者相关并发症和中性粒细胞与淋巴细胞比值关系的研究进展

李 甜    伍 杨    何喜梅    万立平    王学良    苑书婷    席春生   

  1. 730000 兰州，1甘肃中医药大学第一临床医学院
    730050 兰州，2中国人民解放军联勤保障部队第九四〇医院肾脏病科
  • 收稿日期:2023-12-04 修回日期:2024-02-10 出版日期:2024-04-12 发布日期:2024-04-12
  • 通讯作者: 席春生 E-mail:chunshxi@sina.com
  • 基金资助:
    甘肃省卫生健康行业科研计划项目(GSWSKY2022-51)；联勤保障部队第九四〇医院专项课题(2022yxky017)

Research progress in the relationship between hemodialysis-related complications and neutrophil/lymphocyte ratio in hemodialysis patients

LI Tian,  WU Yang,  HE Xi-mei,  WAN Li-ping,  WANG   Xue-liang, YUAN Shu-ting, XI Chun-sheng   

  1. The First Clinical Medical College of Gansu University of Chinese Medicine, Lanzhou 730000, China; 2Department of Nephrology, the 940th Hospital of Joint Logistic Support Force of PLA, Lanzhou 730050, China
  • Received:2023-12-04 Revised:2024-02-10 Online:2024-04-12 Published:2024-04-12
  • Contact: 730050 兰州，2中国人民解放军联勤保障部队第九四〇医院肾脏病科 E-mail:chunshxi@sina.com

摘要： 近年来，中性粒细胞与淋巴细胞比值(neutrophil to lymphocyte ratio,NLR)已被公认为一种新型预测生物标志物，由于其创伤小、经济、简便、敏感性和特异性高等优点，在心血管疾病、肾脏疾病、自身免疫性疾病等预后指标中广泛应用。血液透析(haemodialysis,HD)作为危重症或晚期肾病患者延长寿命的治疗手段，不可避免会导致很多并发症，因此及时识别和治疗HD相关并发症至关重要。有研究发现在HD相关并发症中NLR似乎具有一定的识别和预测能力，故本综述通过总结当前HD患者相关并发症中NLR研究进展，为临床医生评估HD患者相关并发症的发生和预后提供依据。

关键词: 血液透析, 中性粒细胞与淋巴细胞比值, 并发症, 研究进展

Abstract: Currently, neutrophils to lymphocytes ratio(NLR)has been recognized as a new predictive biomarker, and is widely used as a prognostic indicator for cardiovascular diseases, renal diseases, autoimmune diseases and others because it is less traumatic, economic, simple, high sensitive and specific. Hemodialysis (HD) is one of the essential measures for critically ill and end-stage renal disease patients to prolong their lives, but many complications occur inevitably. Early identification and treatment of theses complications are required. Previous studies have found that NLR may have the abilities to recognize and predict HD-related complications. This review summarizes the research progress in NLR changes in HD-related complications, to provide a basis for clinicians to evaluate the presence and prognosis of HD-related complications.

Key words: Hemodialysis, Neutrophil to lymphocyte ratio, Complications, Research progress

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