Abstract: 【Abstract】Chronic kidney disease (CKD) is a syndrome with progressive deterioration of renal function, multisystemic disorders, and higher morbidity and mortality. Patients with CKD have poor quality of life (QOL) and are often plagued by pain, depression, insomnia and multiple comorbidities, causing great pressure on patients as well as their families and increased burden on socio-economic and public health undertakings. At present, the QOL instruments are commonly used, which can be divided into generic instruments and disease-targeted instruments, each with advantages and disadvantages and often clinically used in combination. The factors affecting the QOL in CKD patients are complicated. This paper provides a review of a variety of QOL I nstruments for CKD patients and the related determinants.

Key words: Chronic kidney disease, Quality of life, Assessment, Determinant