Abstract: Maintenance hemodialysis (MHD) patients are often associated with somatic frailty, which leads to a variety of adverse clinical outcomes and causes significant threats to the quality of life and life safety of the patients. Frailty is a complex syndrome usually involving somatic, cognitive and social aspects, which are interconnected and interacted each other. The incidence of somatic frailty is high, and it is usually associated with cognitive and social frailty. The progression of frailty can be alleviated or reversed, if assessment and intervention are made at an early stage. This paper reviews the assessment tools and influencing factors for somatic frailty, with the aim of providing references for the development of frailty interventions for MHD patients in China.

Key words: Maintenance hemodialysis, Somatic frailty, Assessment, Influencing factor