Chinese Journal of Blood Purification ›› 2026, Vol. 25 ›› Issue (02): 138-141.doi: 10.3969/j.issn.1671-4091.2026.02.011

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Patient- reported outcomes and their research and application in hemodiafiltration therapy

ZHAO Dan, Krister Cromm, GAO Wei-jia, LIU Ting-ting, FANG Li-jun, YAN Yu-cheng, GU Le-yi, ZHANG Hai-fen   

  1. 1 Department of Nursing and   4 Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China; 2 Global Medical Office, Fresenius Medical Care, Bad Homburg 61352, Germany; 3 Faculty of Psychology, Technische Universität Dresden, Dresden 01062, Germany; 5 Global Medical Office, Fresenius Medical Care, Shanghai 200030, China
  • Received:2025-06-16 Revised:2025-09-07 Online:2026-02-12 Published:2026-02-02
  • Contact: 200127 上海,上海交通大学医学院附属仁济医院4肾脏科 E-mail:haifenzhang@163.com

Abstract: Patient-reported outcomes (PROs) with regarding to health situation and treatment responses
directly collected from the patients are valuable in nephrology and particularly in hemodialysis (HD), reflecting physical and mental status and helping reform treatment strategies. The comparison of high-dose hemodiafiltration (HDF) with high-flux hemodialysis trial (2018) (CONVINCE) compared high-dose HDF with highflux HD and incorporated PROs for the first time. This review summarizes PRO applications in HDF research
and discusses future clinical implementation.

Key words: Patient reported outcome, Hemodiafiltration, Hemodialysis

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