Abstract: 【Abstract】Objective The aim of this study was to investigate the effects of peritoneal dialysis (PD) and intermittent hemodialysis (IHD) in chronic kidney disease patients complicated with acute kidney injury. Methods We retrospectively reviewed 183 chronic kidney disease patients complicated with acute kidney injury, of whom 35 patients were treated with PD (PD group) and 45 patients with IHD (IHD group). Clinical data including age, sex, type of dialysis, underlying kidney disease, biochemistry indices and dialysis related complications were recorded. Results There were no differences in age, sex, underlying disease and severity of the disease before treatment between the 2 groups (P>0.05). After dialysis, serum creatinine and blood urea nitrogen were higher in PD group than in IHD group (P<0.05), but the survival rate and renal function recovery rate had no differences between the 2 groups. Dialysis related complications were found in 11.4% PD patients similar to the rate in IHD patients (14.0%, P>0.05). Conclusion PD may have the same effect as IHD in the improvement of kidney function in chronic kidney disease patients complicated with acute kidney injury.

Key words: Acute kidney injury, Chronic kidney disease, Hemodialysis