Abstract: 【Abstract】 Objective The aims of this study were to observe nutritional status in hemodialysis (HD) patients, and to evaluate the impact of different nutritional parameters on their prognosis.  Subjects and methods We recruited 97 HD patients with clinically stable state and treated in the HD Center of Peking University Third Hospital during the period from January to June, 2006. Subjective global assessment (SGA), dietary protein intake, biochemistry and anthropometry parameters were collected. They were followed up for 36 months, and outcomes including survival, discontinuing dialysis or death were recorded.  Results During the 36 months of follow-up period, 3 patents were treated with kidney transplantation, one patient changed to peritoneal dialysis, 23 patients died, and 27 patients (28%) withdrew from dialysis. Malnourished patients had significantly higher mortality than well nourished patients (P =0.000). SGA, albumin, dietary protein intake, serum cholesterol, and body-weight index were the independent prognostic risk factors. Area under the ROC curve of SGA was 0.76, and SGA was the best prognostic marker. Results Malnourished HD patients had significantly higher mortality than well nourished patients. SGA, albumin, dietary protein intake, serum cholesterol, and body-weight index were independently associated with mortality. SGA is the most effective prognostic marker, and is simple for nutrition assessment in maintenance hemodialysis patients.

Key words: Dialysis, Nutrition, Prognosis