Abstract: Objective The aim of the study was to discuss the accuracy of online monitoring serum sodium concentration and to observe the effect on water and sodium balance, blood pressure and adverse reaction of the hemodialysis patients who received individualized low-sodium dialysis mode. Method We studied 40 maintenance hemodialysis patients during March 2013 to May 2013 in our Unit. Each patient received individualized low-sodium dialysis after standard sodium dialysis. Clinical indexs including serum sodium concentration and adverse reaction were compared between the two dialysis modes. Results There was no statistical difference in the serum sodium concentration between online monitoring and biochemical method. Compared with the standard sodium dialysis, serum sodium level, systolic blood pressure and degree of thirst were significantly reduced in individualized low-sodium dialysis mode with low incidence of adverse events. Conclusion There was a good correlation between online monitoring serum sodium concentration and conventional biochemical analysis result. Serum sodium level , systolic blood pressure, degree of thirst and interdialytic weight gain could be significantly reduced in individualized low-sodium dialysis mode which shows excellent security with low incidence of adverse events.

Key words: individualized low-sodium dialysis mode, online monitoring serum sodium concentration, serum sodium level