Abstract: Objective Observation of beraprost sodium on elderly patients action and effect of arteriovenous fistula .Methods The study included 82 elderly patients action venous fistula surgery were randomly divided into the beraprost sodium therapy group (n = 42), control group (n = 40) , the success rate of the two groups of arteriovenous fistula , the incidence of complications, fistula after the blood vessels and blood flow changes , blood and coagulation analyzer change, adverse drug reactions , clinical observation and comparison.Results Treatment of arteriovenous fistula after 2 weeks and 4 weeks of success rate (97.6%, 97.6%) higher than in the control group, the difference was statistically significant (x2=12.48 P=0.002; x2=11.72 P=0.014), the treatment group the incidence of postoperative complications (4.8%) than in the control group the incidence of postoperative complications (55%), the difference is statistically significance (x2=21.45 P=0.012), fistula postoperative around blood flow (406.4 ± 106.4) and the control group after around blood flow (228.20 ± 88.6), the difference was statistically significant (F=246.238, P=0.000), the treatment group before and after the blood and the blood coagulation analysis comparison, no significant difference (P>0.05).Conclusion Beraprost sodium can improve the intemal arteriovenous fistula operation success rate in elderly patients and curative effect.

Key words: Beraprost sodium, Elderly patients, Arteriovenous fistula, Success rate, Observation