Abstract: 【Abstract】Objective To explore the choice of surgical methods for renal hyperparathyroidism complicated with thyroid carcinoma. Methods The clinical data including preoperative diagnosis, surgical methods, pathological results and laboratory examinations of the patients with renal hyperparathyroidism complicated with thyroid cancer treated in the Thyroid and Breast Surgery of the 960th Hospital of the People’s Liberation Army from February 2012 to August 2019 were retrospectively analyzed. The patients were followed up for 2～90 months (median follow-up period 60 months). The improvement of clinical symptoms and recurrence were observed. Results In the 480 patients with renal hyperparathyroidism undergoing parathyroidectomy, 16 (3.3%) were found to accompany with thyroid cancer. Surgery was successfully performed in 15 cases, and one case underwent re-operation. Pathologically, all of the 16 thyroid cancer samples were papillary thyroid carcinoma. Total thyroidectomy was performed in the 16 cases, 12 of them received central lymphadenectomy and 2 of them received lateral cervical lymph node dissection. A total of 62 parathyroid glands were resected. The clinical symptoms of the patients relieved after operation, and the related biochemical indexes improved or became normal compared with those before the operation. No recurrence occurred during followup. Conclusion Patients with renal hyperparathyroidism should carefully assess the character of the thyroid lesions before operation. The best surgical effect can be obtained by accurate and appropriate design of the operation area.

Key words: Secondary hyperparathyroidism, Surgery, Thyroid carcinoma