Abstract: 【Abstract】Objective To retrospectively analyze the epidemiology of maintenance hemodialysis (MHD) in Wuhan in the period from 2015 to 2018 in order to provide the supporting data for the improvement of quality control of hemodialysis. Methods Information of the MHD patients registered in the Quality Control System of Dialysis in Wuhan from 2015 to 2018 was retrospectively studied. Age, sex, dialysis age, primary disease, vascular access pathway and cause of death of the patients were analyzed. Results ①The decrease tendency of annual mortality was present in the MHD patients (χ2=22.668，P＜0.001), and
their dialysis age became longer (χ2=18.950, P＜0.001). ②Proportion of the MHD patients died in the first dialysis year became less (χ2=20.069, P＜0.001). ③Diabetes accounted for the highest proportion of primary diseases in death cases (26.4% ), followed by hypertension (25.1% ) and primary glomerulonephritis (22.1%). ④The cause of death was cardiovascular events (25.3%), cerebrovascular events (15.8%), infection (5.9%) and gastrointestinal bleeding (3.6%). ⑤The proportion ofAVF in the middlEaged group (45～59 years old) was significantly higher than that in other age groups, and the proportion ofAVF in the elderly group was the lowest (χ2=45.927, P＜0.001). ⑥ The median survival time ofAVF patients was 40 (65, 20) months, significantly longer than that of 19 (38,9) months in non-AVF patients (χ2=104.818, P＜0.001). Conclusion The annual mortality
rate of MHD patients inWuhan city was decreasing. In the death MHD patients, dialysis age became longer, the most important primary disease was diabetes, the most important cause of death was cardiovascular events, and the survival time was relatively longer inMHDpatients withAVF.

Key words: Maintenance hemodialysis, Mortality, Epidemiology