Abstract: 【Abstract】Objective To investigate the relationship between blood pressure variability (BPV) and hospitalization of hemodialysis patients. Methods A total of 92 patients undergoing maintenance hemodialysis (MHD) in the period between Dec 2012 and Dec 2014 were included in this study. Blood pressure was measured during each visit. Visit-to-visit BPV was quantified by calculating the standard deviation (SD). The hospitalization status of the patients was recorded and the relationship between prEdialysis BPV and the hospitalization status was analyzed. Results The annual hospitalization frequency of the patients with high prEdialysis
systolic BPV was significantly higher than that of the patients with low prEdialysis systolic BPV (t=2.662, P=0.009). PrEdialysis systolic BPV (t=3.007, P=0.003) and prEdialysis diastolic BPV (t=4.431, P＜0.001) were significantly higher in hospitalized patients than in non-hospitalized patients. Logistic regression analysis showed that higher prEdiastolic BPV was the independent risk factor for hospitalization (OR=2.694, 95% CI1.034~7.023, P=0.043). Conclusion The visit-to-visit BPV was related to hospitalization in MHD patients. Controlling prEdialysis BPV, especially the prEdiastolic BPV, may help reduce hospitalization rate in MHD patients.

Key words: Hemodialysis, Blood pressure variability, Hospitalization