中国血液净化

中国血液净化 ›› 2021, Vol. 20 ›› Issue (05): 333-335.doi: 10.3969/j.issn.1671-4091.2021.05.011

• 综述 • 上一篇    下一篇

氧化应激在腹膜透析患者胰岛功能损伤中的作用

边帆1,葛勤敏1,蒋更如1   

  1. 1上海交通大学医学院附属新华医院肾内科
  • 收稿日期:2020-11-26 修回日期:2021-02-01 出版日期:2021-05-12 发布日期:2021-05-06
  • 基金资助:
    基金课题上海市卫生和计划生育委员会科研课题(201740081)

Effects of oxidative stress on islet dysfunction in peritoneal dialysis patients

  1. 1 Department of Nephrology 1Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
  • Received:2020-11-26 Revised:2021-02-01 Online:2021-05-12 Published:2021-05-06
  • Contact: Geng-ru JIANG E-mail:jianggeng-ru@hotmail.com

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摘要： 【摘要】腹膜透析是治疗终末期肾病的有效方法之一。随着透析人口数量和透龄的增长，腹膜透析后新发糖尿病报道日益增多，其发生机制尚不明确。本文就腹膜透析患者的氧化应激状况与胰岛功能损伤进行综述，为进一步认识腹膜透析患者新发糖尿病的机制、临床预防和治疗提供理论依据。

关键词: 腹膜透析, 新发糖尿病, 氧化应激, 胰岛β细胞

Abstract: 【Abstract】Peritoneal dialysis (PD) is one of the effective methods to treat end-stage renal disease. With the increase of dialysis population and dialysis age, reports about the new onset diabetes mellitus after PD increased significantly. In this paper, the oxidative stress and islet dysfunction in PD patients are analyzed to provide a theoretical basis for further understanding the mechanism and for clinical prevention and treatment of new onset diabetes mellitus in PD patients.

Key words: Peritoneal dialysis, New onset diabetes mellitus, Oxidative stress, Islet β cell

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