中国血液净化

中国血液净化 ›› 2023, Vol. 22 ›› Issue (12): 916-919.doi: 10.3969/j.issn.1671-4091.2023.12.007

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炎症因子在血液透析患者合并抑郁中的研究进展

张顺娟   夏运风   

  1. 400016 重庆，1重庆医科大学附属第一医院肾脏内科
  • 收稿日期:2023-07-31 修回日期:2023-09-15 出版日期:2023-12-12 发布日期:2023-11-30
  • 通讯作者: 夏运风 E-mail:xyf0920@126.com

Research progresses in inflammatory factors in hemodialysis patients complicated with depression

ZHANG Shun-juan, XIA Yun-feng   

  1. Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
  • Received:2023-07-31 Revised:2023-09-15 Online:2023-12-12 Published:2023-11-30
  • Contact: 400016 重庆，1重庆医科大学附属第一医院肾脏内科 E-mail:xyf0920@126.com

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摘要： 血液透析是慢性肾脏病进展至终末期最主要的替代治疗方法。据报道，血液透析患者中抑郁的发病率达20%～55%。近些年研究表明炎症因子在透析患者的病理生理机制上有重要作用，并对其抑郁的发生发展有影响，现就炎症因子在血液透析患者抑郁中的作用机制及其治疗相关进展进行综述。

关键词: 血液透析, 炎症因子, 抑郁, 发病机制, 治疗

Abstract: Hemodialysis is the most important replacement treatment for chronic kidney disease progressed to end-stage renal disease. The incidence of depression has been reported to be 20～55% in hemodialysis patients. Recent studies have shown that inflammatory factors play important roles in hemodialysis patients, and have impacts on the presence and development of depression. This article reviews the research progresses in inflammatory factors in the pathogenesis of depression in hemodialysis patients and its treatment.

Key words: Hemodialysis, Inflammatory factor, Depression, Pathogenesis, Treatment

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