中国血液净化

中国血液净化 ›› 2024, Vol. 23 ›› Issue (01): 50-52.doi: 10.3969/j.issn.1671-4091.2024.01.011

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术中甲状旁腺激素测定在继发性甲状旁腺功能亢进手术中的临床研究进展

连丽新   高文超   李同昌   吕文超   李晓阳   齐 明   

  1. 150010 哈尔滨，1哈尔滨市第一医院普外四科
  • 收稿日期:2023-09-28 修回日期:2023-11-04 出版日期:2024-01-12 发布日期:2024-01-12
  • 通讯作者: 齐明 E-mail:qm1301@163.com
  • 基金资助:
    黑龙江省卫生健康委科研课题(2019-212)

Research progresses in the intraoperative parathyroid hormone determination during the operation for secondary hyperparathyroidism

LIAN Li-xin, GAO Wen-chao, LI Tong-chang, Lyu Wen-chao, LI Xiao-yang, QI Ming   

  1. The Fourth General Surgery Department, The First Hospital of Harbin, Harbin 150000, China
  • Received:2023-09-28 Revised:2023-11-04 Online:2024-01-12 Published:2024-01-12
  • Contact: 150010 哈尔滨，1哈尔滨市第一医院普外四科 E-mail:qm1301@163.com

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摘要： 甲状旁腺切除术能够有效治疗继发性甲状旁腺功能亢进症(secondary hyperparathyro idism,SHPT)，但由于甲状旁腺解剖生理学特点，存在手术中无法完全切除所有甲状旁腺腺体导致近期或远期复发的风险。术中甲状旁腺激素(intraoperative parathyroid hormone,ioPTH)测定的应用已被证实在提高手术有效性和安全性、降低手术后复发率和并发症等方面具有重要价值，但目前仍未统一监测标准。本文旨在阐述ioPTH在SHPT患者甲状旁腺切除术中应用的研究进展及现状，为临床手术治疗SHPT提供更多的理论依据与研究方向。

关键词: 术中甲状旁腺激素, 继发性甲状旁腺功能亢进症, 甲状旁腺切除术

Abstract: Parathyroidectomy can effectively treat the secondary hyperparathyroidism (SHPT). However, complete resection of the parathyroid glands during operation is often impossible due to the anatomical and physiological characteristics of parathyroid glands. Thereby the risk of short-term or long-term recurrence increases. Intraoperative parathyroid hormone (ioPTH) determination has been proven to be of great value in improving effectiveness and safety of the surgery and in reducing the recurrence and complications after the surgery. However, there is no consensus on determination standard. This paper aims to review the research progresses and current status of ioPTH during parathyroidectomy surgery for SHPT and to provide more theoretical bases and research targets for SHPT surgery.

Key words: Intraoperative parathyroid hormone, Secondary hyperparathyroidism, Parathyroidectomy

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