中国血液净化

中国血液净化 ›› 2021, Vol. 20 ›› Issue (08): 525-530.doi: 10.3969/j.issn.1671-4091.2021.08.006

• 临床研究 • 上一篇    下一篇

透析中运动对维持性血液透析患者运动能力和透析效率影响的Meta分析

于新涛1,曹松梅2,吉小静1   

  1. 1江苏省苏北人民医院血液净化中心
    2江苏大学附属医院护理部
  • 收稿日期:2021-02-25 修回日期:2021-05-24 出版日期:2021-08-21 发布日期:2021-08-05
  • 通讯作者: 曹松梅 caosongmei75@126.com E-mail:caosongmei75@126.com

The effects of intradialytic exercise on athletic ability and dialysis adequacy in maintenance hemodialysis patients: a meta-analysis

  1. 1 Blood Purification Center, Northern Jiangsu People’s Hospital, Yangzhou 225001, China;  2 Nursing Department, the Affiliated Hospital of Jiangsu University, Zhenjiang 212013, China
  • Received:2021-02-25 Revised:2021-05-24 Online:2021-08-21 Published:2021-08-05
  • Contact: cao songmei E-mail:caosongmei75@126.com

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摘要： 【摘要】目的系统评价透析中运动对维持性血液透析患者运动能力和透析效率的影响。方法计算机检索PubMed、Embase、Web of Science、Cochrane Library、CNKI、VIP、WanFang Data 等数据库中对维持性血液透析患者进行透析中运动干预的随机对照试验，检索时限截至2020 年7 月。由2 位研究者根据纳入与排除标准进行文献筛选、资料提取和质量评价后，采用RevMan 5.3 软件进行Meta 分析。结果最终纳入文献22 篇，共计1057 例患者。Meta 分析结果显示：透析中运动组在延长6min 步行距离[MD=69.070，95% CI (54.710～83.440), P＜0.001]、缩短10 次坐立时间[SMD=- 0.770，95%CI(- 1.170～- 0.380), P＜0.001]、提高峰值摄氧量[SMD=0.460，95% CI(0.070～0.850),P=0.020]、提高Kt/V[MD=0.090，95%CI(0.020～0.170),P=0.010]方面均明显优于对照组。结论透析中运动可增强患者运动能力，提高透析效率。

关键词: 血液透析, 透析中运动, 运动能力, 透析效率, Meta分析

Abstract: 【Abstract】Objective To systematically evaluate the effects of intradialytic exercise on athletic ability and dialysis adequacy in maintenance hemodialysis (MHD) patients. Methods The databases of PubMed, Embase, Web of science, Cochrane Library, CNKI, VIP and WanFang were retrieved from the establishment of the database to July 2020 for the randomized controlled trials of intradialytic exercise. Two investigators screened the literature according to the inclusion and exclusion criteria. After data extraction and quality assessment, the software of RevMan 5.3 was used for meta-analysis. Results A total of 22 studies which included 1,057 participants were analyzed. Meta-analysis showed that the intradialytic exercise group had better outcomes than the control group in 6-minute walk distance (MD=69.070, 95% CI 54.710~83.440, P＜0.001), 10 sit- to- stand- to- sit cycles (SMD=- 0.770, 95% CI~1.170~- 0.380, P＜0.001), peak oxygen uptake (VO2peak) (SMD=0.460, 95% CI 0.070~0.850, P=0.020), and Kt/V (MD=0.090, 95% CI 0.020~0.170, P=0.010). Conclusion Intradialytic exercise can enhance athletic ability and improve dialysis adequacy in MHD patients.

Key words: Hemodialysis, Intradialytic exercise, Athletic ability, Dialysis adequacy, Meta-analysis

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