中国血液净化 ›› 2017, Vol. 16 ›› Issue (08): 509-511.doi: 10.3969/j.issn.1671-4091.2017.08.002

• 专题与讲座 • 上一篇    下一篇

红细胞生成素低反应的原因及对策

桂定坤1,汪年松1   

  1. 1. 上海交通大学附属第六人民医院肾内科
  • 收稿日期:2017-01-04 修回日期:2017-06-22 出版日期:2017-08-12 发布日期:2017-08-12
  • 通讯作者: 汪年松 wangniansong2012@163.com E-mail:wangniansong2012@163.com
  • 基金资助:

    国家自然基金面上项目(81270824,81670657)、“十二五”国家科技支撑计划(2013BAI02B04)

Causes and management of low responses to erythropoietin

  • Received:2017-01-04 Revised:2017-06-22 Online:2017-08-12 Published:2017-08-12
  • Contact: Nian-song wang E-mail:wangniansong2012@163.com

摘要: 红细胞生成素(erythropoietin,EPO)临床是应用于慢性肾脏病患者贫血治疗,一部分患者因铁缺乏、炎症、氧化应激等因素出现红细胞生成素低反应的现象,影响红细胞生成素治疗效果,充分透析、补充营养、使用长效红细胞生成素等对策可改善红细胞生成素低反应。

关键词: 血液净化, 红细胞生成素, 慢性肾脏病

Abstract: Erythropoietin (EPO) is used in clinical treatment of anemia in chronic kidney disease patients. Hyporesponsiveness of EPO occurs in some patients due to iron deficiency, inflammation, oxidative stress, etc. Adequate dialysis, improvement of nutritional status, and the use of long-acting EPO may have effect on the EPO hyporesponsiveness.

Key words: Blood purification, Erythropoietin, Chronic kidney disease