中国血液净化

中国血液净化 ›› 2017, Vol. 16 ›› Issue (08): 516-518.doi: 10.3969/j.issn.1671-4091.2017.08.004

• 专题与讲座 • 上一篇    下一篇

持续性腹膜透析患者体内维生素D的含量对铁代谢的影响

李虹达1,任野平1   

  1. 1. 哈尔滨医科大学第二附属医院肾内科
  • 收稿日期:2017-04-17 修回日期:2017-06-07 出版日期:2017-08-12 发布日期:2017-08-12
  • 通讯作者: 任野平 renyeping123@126.com E-mail:591146029@qq.com

The influence of vitamin D level on iron metabolism in patients on continuous ambulatory peritoneal dialysis

  • Received:2017-04-17 Revised:2017-06-07 Online:2017-08-12 Published:2017-08-12

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摘要： 持续性不卧床腹膜透析(continuous ambulatory peritoneal dialysis，CAPD)患者维生素D 缺乏或不足的患病率极高，由于维生素D 的缺乏加重了CAPD 患者体内骨矿物质代谢的异常、微炎症反应及营养状态的异常，从而导致体内铁调素(hepcidin)的蓄积，加重患者体内的铁代谢紊乱。我们通过对CAPD 患者补充维生素D，从而改善患者体内的异常代谢状态及营养情况，减少hepcidin 的蓄积，可能对CAPD患者铁代谢的异常有一定治疗价值。

关键词: 腹膜透析, 维生素D, 铁代谢

Abstract: The prevalence of vitamin D deficiency or inadequate vitamin D intake is very high in patients on continuous ambulatory peritoneal dialysis (CAPD). Iron metabolism disturbance is aggravated due to the accumulation of hepcidin, which is resulted from the vitamin D deficiency induced abnormal bone mineral metabolism, micro-inflammation and malnutrition in CAPD patients. Supplement of vitamin D may be useful for iron metabolism disturbance through improvement of abnormal metabolism and malnutrition status and decrease of hepcidin in CAPD patients.

Key words: Peritoneal dialysis, Vitamin D, Iron metabolism