中国血液净化 ›› 2018, Vol. 17 ›› Issue (08): 505-507.doi: 10.3969/j.issn.1671-4091.2018.08.001

• 专题 •    下一篇

腹膜透析患者心脑血管疾病的危险因素

韩庆烽   

  1. 北京大学第三医院肾脏内科
  • 收稿日期:2018-02-22 修回日期:2018-03-06 出版日期:2018-08-12 发布日期:2018-08-12

Risk factors for cardio- and cerebro- vascular disease in peritoneal dialysis patients

  • Received:2018-02-22 Revised:2018-03-06 Online:2018-08-12 Published:2018-08-12

摘要: 【摘要】心脑血管疾病是腹膜透析患者死亡的首要因素,多种危险因素参与腹膜透析患者的心脑血管疾病发病过程。这些危险因素可以分为3 类,①不良的生活方式,包括缺乏运动、高盐饮食和吸烟;②尿毒症并发症或合并症,包括高血压、糖尿病、炎症状态,蛋白质-能量消耗、贫血、慢性肾脏病-矿物质骨病、低钾血症和高脂血症;③腹膜透析不充分,包括残余肾功能下降和容量负荷过重等。应当遵循多个学科的临床实践指南,结合腹膜透析治疗的特殊规律,有效地预防和处理腹膜透析患者的各种心脑血管危险因素。

关键词: 心脑血管危险因素, 腹膜透析

Abstract: 【Abstract】Cardio- and cerebro-vascular disease is a primary cause of death in peritoneal dialysis (PD) patients. A variety of risk factors are involved in the pathogenesis of cardio- and cerebro-vascular disease in PD patients. These risk factors can be classified into three categories: ①poor lifestyles, including lack of physical activity, high salt diet, and smoking; ②uremic complications or comorbidities, including hypertension, diabetes, inflammatory status, protein-energy wasting, anemia, chronic kidney disease-mineral bone disease, hypokalemia, and hyperlipidemia; and ③inadequate peritoneal dialysis, including decreased residual renal function, and volume overload. These risk factors should be effectively prevented and managed in PD patients based on the guide of multi-disciplinary clinical practice and the characteristics of PD.

Key words: Risk factors for cardio- and cerebro-vascular disease, Peritoneal dialysis