中国血液净化

中国血液净化 ›› 2021, Vol. 20 ›› Issue (05): 343-346.doi: 10.3969/j.issn.1671-4091.2021.05.014

• 综述 • 上一篇    下一篇

透析患者蛋白质能量消耗与不良临床结局的研究进展

孟霞1,方敬爱2,孙艳艳2,刘文媛2,张晓东2,常沁涛2,王蕊花2   

  1. 1山西医科大学第一临床医学院
    2山西医科大学第一医院肾脏内科

  • 收稿日期:2020-11-19 修回日期:2021-02-07 出版日期:2021-05-12 发布日期:2021-05-06
  • 通讯作者: 孙艳艳 yanyansun6839@126.com E-mail:yanyansun6839@126.com

Research progress in the adverse outcome of dialysis patients with protein energy wasting

  1. 1The First Clinical Medical College of Shanxi Medical University, Taiyuan 030000, China;  2Department of Nephrology, Shanxi Medical University First Hospital, Taiyuan 030000, China
  • Received:2020-11-19 Revised:2021-02-07 Online:2021-05-12 Published:2021-05-06
  • Contact: Sun Yanyan E-mail:yanyansun6839@126.com

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摘要： 【摘要】蛋白质能量消耗(protein energy wasting,PEW)在尿毒症透析患者中普遍存在，往往会导致多种不良临床结局，加大了住院和死亡风险。本文就近几年国内外关于PEW 与死亡率、心血管疾病、感染、衰弱、生活质量及抑郁、红细胞生成素(erythropoietin,EPO)低反应等不良临床结局的相关研究作一综述，以期为引起临床重视、早期发现、早期干预提供理论依据。

关键词: 蛋白质能量消耗, 腹膜透析, 血液透析, 临床结局

Abstract: 【Abstract】Protein energy wasting (PEW) is a common abnormality among uremic patients with dialysis, often leading to adverse clinical outcomes including the risk of hospitalization and mortality. This paper reviews the recent progress from China and foreign countries in PEW on clinical outcomes such as mortality, cardiovascular disease, infection, frailty, lower quality of life, depression, and insensitivity to erythropoietin, in order to provide theoretical bases for the awareness, early detection and intervention of PEW in dialysis patients.

Key words: Protein energy wasting, Peritoneal dialysis, Hemodialysis, Clinical outcome

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