中国血液净化

›› 2005, Vol. 4 ›› Issue (1): 14-15.

• 论著 • 上一篇    下一篇

维持性血液透析患者血管通路血流量递减与Kt/V及尿素清除率定量分析 

韦 洮 张大伟 赵青艺 檀 敏 蔡美顺 杨洪杰 于仲元   

  1. 100044 北京，北京大学人民医院肾内科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2005-01-12 发布日期:2005-01-12

  • Received:1900-01-01 Revised:1900-01-01 Online:2005-01-12 Published:2005-01-12

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摘要：

目的 通过测定维持性透析患者血管通路血流量、Kt/V值及尿素清除率（URR）的定量分析，进 一步探讨血流量对透析充分性的影响。方法 本研究选择慢性维持性血液透析患者80例。设定血液透析开始后在线血流量，根据血流量不同分为3组，I组血流量300ml/min，Ⅱ组血流量250ml/min，Ⅲ组血流量200ml/min，计算各组Kt/V值与尿素减少率，观察血流量与Kt/V值及尿素减少率之间的相关关系。结果 3组之间Kt/V、URR比较 P<0.001，差异均具有显著性；血流量与 Kt/V、URR 之间呈正相关 (r1 = 0.448, P<0.001; r2=0.413, P<0.001) 随着血流量从 300 ml/min降到200 ml/min，Kt/V、URR分别从(1.33±0.33)、(68.19±8.86)%降到(0.99±0.31)、(58.59±13.19)%，分别降低25.56%、14.08%。结论 进一步从定量水平明确血液透析患者的血流量与Kt/V、URR密切相关，透析时保证足够的血流量是透析患者综合临床状况分析的一项重要指标。

关键词: 维持性血液透析, Kt/V, 血流量, 尿素减少率

Abstract:

Objective To understand the effect of blood flows on dialysis adequacy by measuring blood flow of access,Kt/V and urea reduction ratio (URR) of maintenance hemodialysis patients. Methods The blood flow of access, Kt/V and URR at the beginning of one hemodialysis session were observed and calculated. The relationship between the blood flow of access and Kt/V and URR were analyzed. Results We found that there was a significant positive correlation between the blood flow of access and Kt/V and URR (r1=0.448, P<0.001; r2=0.413, P<0.001 respectively). As the blood flow reduced from 300 ml/min to 200 ml/min, Kt/V and URR reduced from 1.33±0.33、(68.19±8.86)% to 0.99±0.31、(58.59±13.19)% respectively, reduced 25.56%、14.08%. Conclusion The blood flow of access of the chronic maintenance hemodialysis patients is a valuable index of the hemodialysis quality. 

Key words: Kt/V, Blood flowed volume, Urea reduction ratio (URR) 

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