中国血液净化

中国血液净化 ›› 2020, Vol. 19 ›› Issue (12): 843-846.doi: 10.3969/j.issn.1671-4091.2020.12.013

• 综述 • 上一篇    下一篇

血液透析滤过的临床应用进展

张臻1,丁小强1   

  1. 1复旦大学附属中山医院肾内科
  • 收稿日期:2020-07-20 修回日期:2020-09-14 出版日期:2020-12-12 发布日期:2020-12-08
  • 通讯作者: 丁小强 ding.xiaoqiang@zs-hospital.sh.cn E-mail:ding.xiaoqiang@zs-hospital.sh.cn

Progress towards clinical applications of hemodiafiltration

  1. 1Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
  • Received:2020-07-20 Revised:2020-09-14 Online:2020-12-12 Published:2020-12-08
  • Contact: 丁 丁小强小强 E-mail:ding.xiaoqiang@zs-hospital.sh.cn

PDF

1157

摘要： 【摘要】终末期肾病(end stage renal disease，ESRD)是世界范围内重大的公共健康问题。血液透析滤过(hemodiafiltration，HDF)结合了扩散和对流的方法，可有效清除低分子量和中分子量溶质。随着透析膜材料、超滤控制系统和水处理技术的进步，HDF 已成为一项方便、安全、成熟的治疗技术，最新的临床研究结果证实了HDF可能通过更有效的溶质清除和/或低温效应降低ESRD 患者死亡率，改善预后。

关键词: 血液透析, 血液透析滤过, 终末期肾病

Abstract: 【Abstract】End-stage renal disease (ESRD) is a global healthcare burden. Hemodiafiltration (HDF)is capable of effective clearance of solutes of low and middle molecular weight by combining diffusion and convection. With the improvement of dialyzer membrane and the progress of ultrafiltration control system and water treatment techniques, HDF is currently an accessible, safe and well- established treatment option. Latest clinical evidence demonstrated that HDF can reduce mortality of ESRD patients by superior solutes clearance and/or cooling effect.

Key words: Hemodialysis, Hemodiafiltration, End-stage renal disease

中图分类号: