中国血液净化

中国血液净化 ›› 2024, Vol. 23 ›› Issue (03): 193-196.doi: 10.3969/j.issn.1671-4091.2024.03.008

• 综述 • 上一篇    下一篇

连续性肾脏替代治疗净超滤强度对重症患者预后影响的研究进展

唐友丽    杨莹莹    张  凌   

  1. 成都 610041，1四川大学华西医院肾脏内科/四川大学华西医院肾脏病研究所  
    成都 611130，2成都市温江区人民医院重症医学科
  • 收稿日期:2023-11-14 修回日期:2023-12-02 出版日期:2024-03-12 发布日期:2024-03-12
  • 通讯作者: 杨莹莹 E-mail:yingyingyangsf@163.com

Research progress on the prognostic influence of net ultrafiltration intensity in critically ill patients receiving continuous renal replacement therapy

TANG You-li, YANG Ying-ying, ZHANG Ling   

  1. Department of Nephrology and Kidney Research Institute, West China Hospital, Sichuan University, Chengdu 610041, China; 2Department of Critical Care Medicine, Wenjiang District People's Hospital, Chengdu 611130, China
  • Received:2023-11-14 Revised:2023-12-02 Online:2024-03-12 Published:2024-03-12
  • Contact: 成都 610041，1四川大学华西医院肾脏内科/四川大学华西医院肾脏病研究所 E-mail:yingyingyangsf@163.com

摘要： 连续性肾脏替代治疗(continuous renal replacement therapy，CRRT)期间净超滤(net ultrafiltration，UFNET)常用于治疗危重患者的容量过负荷(fluid overload，FO)，但UFNET强度对重症患者预后的影响尚不清楚。本文从容量负荷对危重患者的影响、不同强度UFNET对器官功能、死亡率、透析依赖等的影响，以及可能用于CRRT期间指导调整UFNET的潜在工具等方面进行综述，以引起临床医生对CRRT治疗期间最佳净超滤强度的关注。

关键词: 连续性肾脏替代治疗, 净超滤, 急性肾损伤, 容量负荷

Abstract: Net ultrafiltration (UFNET) during continuous renal replacement therapy (CRRT) is often used to treat fluid overload (FO) in critically ill patients, but the effect of UFNET intensity on the prognosis of critically ill patients remains unclear. This article reviews the effects of FO on critically ill patients and the effects of different levels of UFNET on organ function, mortality, dialysis dependence, and potential tools that may be used to guide the adjustment of UFNET to draw clinicians' attention to the optimal UFNET intensity during CRRT treatment.

Key words: Continuous renal replacement therapy, Net ultrafiltration, Acute kidney injury, Fluid overload

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