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Chinese Journal of Blood Purification

    12 November 2012, Volume 11 Issue 11 Previous Issue    Next Issue
    Peritoneal dialysis in uremic patients on C-reactive protein levels and its clinical significance II
    2012, 11 (11):  0-0. 
    Abstract ( 276 )   HTML ( 3 )  
    Objective To discuss the effect of peritoneal dialysis to C-reactive protein (CRP) of uraemic patients and the relation between inflammation and malnutrition, anemia and cardio-cerebrovascular diseases. Method Detection of C-reaction protein (CRP), serum albumin (Alb), hemoglobin (Hb),serum creatinine(Scr)of healthy control subjects, non-dialysis uraemic patients and continuous ambulatory peritoneal dialysis (CAPD) patients, and then divide them into normal group (CRP<10mg/L) and abnormal group (CRP>10mg/L) according to the CRP level of CAPD patients. Results The CRP level of both non-dialysis uraemic group and CAPD group are higher than that of healthy control group (P<0.001) while the CRP level of CAPD group is higher than non-dialysis uraemic group(P<0.01).The CRP level of CAPD patients is negatively associated with Alb and Hb (P<0.01),The probability to have cardio-cerebrovascular disease of elevated CRP level group is higher than normal group (P<0.05). Conclusions CAPD patients have inflammation with a rising CRP level, and this probability is higher than that of non-dialysis uraemic patients. Inflammation plays a role in malnutrition and anemia of CAPD patients, and it also has something to do with cardio-cerebrovascular disease of CAPD patients.
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    Relationship between outpatientfollow-up frequency and survivalin peritoneal dialysis patients
    2012, 11 (11):  596-599. 
    Abstract ( 195 )   HTML ( 0 )   PDF (217KB) ( 195 )  
    Objective To investigate the relationshipbetween outpatient follow-up frequency and survival in peritoneal dialysis (PD) patients, and its influential factors. MethodThe study enrolled 202 incident patients who started PD between September 2006 and September 2008.All of them was divided into two groups according to outpatientfollow-up frequency, one group who were followed up once a month,and the other group who were followed up more than one month.The general information and clinical data were reviewed retrospectively, includinglaboratory indexes,nutrition state, comorbidities,and outcome. ResultsThere were no significant differences between two groups on thebaseline, exceptthe proportion of residence inrural(p=0.005). At the end-point of research, the groupwho were followed up more than one month had higher incidenceof hypertension (p=0.000),lower of serum albumin (p=0.028), higher of serum phosphorus(p=0.001), and higher incidenceof malnutrition evaluated by SGA (p=0.046). Kaplan-Meier survival analysis had shown that the groupwho were followed up once a month had higher patient survival and technical survival than the groupwho wre followed up more than one month significantly (p=0.001, p=0.002).ConclusionThe outpatient follow-uponce a month can result inbetterprognosis in PD patients.
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    Sagliker syndrome complicated with maintenace peritoneal dialysis patient:a case report.
    2012, 11 (11):  605-605. 
    Abstract ( 180 )   HTML ( 0 )   PDF (108KB) ( 182 )  
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    Comparing continuous venovenous hemofiltration and automated peritoneal dialysis in MODS patients with acute kidney injury
    2012, 11 (11):  611-615. 
    Abstract ( 218 )   HTML ( 0 )   PDF (219KB) ( 261 )  
    [Abstract] Objective To investigate the role of APD in MODS with AKI patients requiring continuous renal replacement therapies. Methods Retrospectively reviewed MODS with AKI cases treated with APD(Group A) or CVVH(Group B) from 2010 January to 2011 March. The clinical characteristics,causative of AKI,treatment modalities,and outcomes were analyzed and compared with these two groups.Results Group A and group B comprised 14 cases and 19 cases respectively. There were no significant differences between two groups in baseline clinical characteristics. Furthermore, The groups were similar in metabolic control and correction of fluid overload. BUN,serum creatinine, and bicarbonate levels were stabilized after 72h treatment procedure. Mortality was 75% in group A and 78.9% in group B(P=0.68). There was no significant difference in infectious complications rate between two groups. Cost of disposables was higher in group B than in group A.Conclusions APD may be a safe, effective and low cost alternative to renal replacement therapy in MODS with AKI.
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    Risk factors and prognosis of peritoneal dialysis complicating with abdominal wall hernia
    2012, 11 (11):  615-620. 
    Abstract ( 285 )   HTML ( 1 )   PDF (254KB) ( 213 )  
    Objective: To investigate the risk factors and outcome of the Peritoneal dialysis (PD) patients with abdominal wall hernia. Methods: We recruited 436 PD patients from Shanghai Ruijin Hospital. Baseline characteristics and follow-up data were recorded. All the participants were divided into Group A (normal group, n = 409) and Group B (hernia group, n = 27) based on whether abdominal wall hernia occurred. Logistic regression analysis was performed. Results: The hernia rate was 6.2% (30 events). The incidence of hernia was 0.054 times/patient years and the average time of first hernia was 21.86 ± 27.58 weeks. Among all patients, 22 were inguinal hernia (81.48%), 2 were incisional hernia(7.4%), 2 were umbilical hernia(7.4%) and 1 was multiple hernia(3.7%). There were similar diabetes (27.62% vs 22.22%), polycystic kidney disease (1.5% vs 0) and laparoscopic implantation of catheter (8.31% vs 18.51%) in two groups. Patients in group A were younger (59.33 ± 17.73 vs 65.07 ± 13.27), less male (54.27% vs 85.16%), less abdominal surgery history (19.32% vs. 37.04%) and higher body mass index (BMI) (22.53 ± 3.52 vs 20.96 ± 2.38) than group B (P <0.05). Two groups had similar baseline characterics. Patients in group A had higher serum creatinine (697.00 ± 370.50 vs 545.50 ± 338.75,) and triglycerides (1.56 ± 1.24 vs 0.98 ± 0.92) levels than group B. Serum creatinine (OR=0.993, P=0.04) and triglyceride (OR=0.084, P=0.04) were negatively correlated with hernia. Conclusion: Inguinal hernia is the most common type of abdominal wall hernia in PD patients. Previous abdominal surgery, smaller body size, older men and poor nutritional status were the risk factors of PD complicating with hernia.
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