中国血液净化

中国血液净化 ›› 2017, Vol. 16 ›› Issue (10): 696-698.doi: 10.3969/j.issn.1671-4091.2017.010.014

• 综述 • 上一篇    下一篇

在线血液透析滤过的临床获益与研究进展

熊瑞芳1,路香雪1,李寒1,王世相1   

  1. 1. 首都医科大学附属北京朝阳医院血液净化科 首都医科大学肾病学系
  • 收稿日期:2017-06-26 修回日期:2017-08-28 出版日期:2017-10-12 发布日期:2017-10-12
  • 通讯作者: 李寒 hanli@ccmu.edu.cn E-mail:hanli@ccmu.edu.cn
  • 基金资助:

    国家自然科学基金(81670673)；国家自然科学基金(81200543)；北京市卫生系统高层次卫生技术人才培养资助项目(2013-3-016)

Clinical benefit and research progress of online hemodiafiltration

  • Received:2017-06-26 Revised:2017-08-28 Online:2017-10-12 Published:2017-10-12

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摘要： 在线血液透析滤过是一种重要的肾脏替代治疗方法，其结合了血液透析与血液滤过的特点，通过在线生成超净置换液实现对体内毒素的清除，极大提高了对毒素的清除能力，有利于维持透析过程中血流动力学的稳定，对透析患者心血管系统具有一定保护作用。本文主要就在线血液透析滤过的临床获益及研究进展进行综述。

关键词: 在线血液透析滤过, 血液透析, 毒素清除, 心血管保护, 生存率

Abstract: On- line hemodiafiltration（OL-HDF）is an important method of renal replacement therapy, which combines hemodialysis and hemofiltration characteristics. The ultra-net replacement fluid is generated on line and it greatly improved the ability to remove toxins in the body. Meanwhile, it is conducive to maintaining the stability of hemodynamics during dialysis and has a protective effect on the cardiovascular system of dialysis patients. In this review, we summarize the clinical benefit and research progress of OL-HDF.

Key words: on-line HDF, hemodialysis, toxin removal, cardiovascular protection, survival rate