中国血液净化 ›› 2017, Vol. 16 ›› Issue (07): 433-436.doi: 10.3969/j.issn.1671-4091.2017.07.001

• 综述与讲座 •    下一篇

包裹性腹膜硬化的研究进展

王伊娜1,赵慧萍1   

  1. 1. 北京大学人民医院肾内科
  • 收稿日期:2017-01-25 修回日期:2017-03-18 出版日期:2017-07-12 发布日期:2017-07-14
  • 通讯作者: 赵慧萍 huipingzhao2009@163.com E-mail:huipingzhao2009@163.com

The research progress in encapsulating peritoneal sclerosis

  • Received:2017-01-25 Revised:2017-03-18 Online:2017-07-12 Published:2017-07-14

摘要: 包裹性腹膜硬化(encapsulating peritoneal sclerosis,EPS)是长期腹膜透析患者少见的严重并发症,病死率高。EPS 是慢性、隐匿性发生的疾病,早期通常不易识别。临床表现为腹膜进行性纤维样增厚、硬化,导致肠包裹,继而出现部分或完全性肠梗阻。目前其发生机制尚不明确,暂缺乏特异性疗法,需多学科联合治疗。本文将就包裹性腹膜硬化的发病机制、诊疗的研究进展做一介绍。

关键词: 腹膜透析, 包裹性腹膜硬化

Abstract: Encapsulating peritoneal sclerosis (EPS) is a rare but devastating complication with high mortality rate in long- term peritoneal dialysis patients. It is characterized by progressive and extensive fibrotic thickening and sclerosis of the peritoneum, leading to encapsulation of bowel and intestinal obstruction, but is hard to be recognized at its early stage. The pathogenesis of EPS remains elusive. No specific treatment has been developed, and a multidisciplinary combination therapy is adopted at the present time. In this paper, we introduce the pathogenesis, diagnosis and treatment of EPS.