中国血液净化 ›› 2018, Vol. 17 ›› Issue (12): 798-800.doi: 10.3969/j.issn.1671-4091.2018.12.002

• 专题与讲座 • 上一篇    下一篇

腹膜透析治疗急性肾损伤的研究进展

金海姣1,倪兆慧1   

  1. 1. 上海交通大学医学院附属仁济医院肾脏科
  • 收稿日期:2018-07-23 修回日期:2018-08-08 出版日期:2018-12-12 发布日期:2018-12-19
  • 通讯作者: 倪兆慧 profnizh@126.com E-mail:profnizh@126.com
  • 基金资助:

    上海市卫生和计划生育委员会科研课题(201740037);上海交通大学医学院附属仁济医院临床科研创新培育基金(PYIII-17-009)

Peritoneal dialysis in acute kidney injury

  • Received:2018-07-23 Revised:2018-08-08 Online:2018-12-12 Published:2018-12-19

摘要: 【摘要】腹膜透析(peritoneal dialysis,PD)是急性肾损伤(acute kidney injury,AKI)进行肾脏替代治疗的适当方法。软性PD 导管是PD 治疗AKI 时建立透析通路的金标准。目前尚无公认的最优PD 治疗AKI 时的植管方法。对于稳定的AKI 患者,PD 治疗时每周Kt/V 目标值最低标准可设为2.1。对于危重患者,PD 治疗时每周Kt/V 目标值可设为3.5。在采用高容量腹膜透析(high volume peritoneal dialysis, HVPD)治疗AKI 时,自动化腹膜透析(automated peritoneal dialysis, APD)更能节省人力,较手工PD具有明显优势。然而,PD 治疗AKI 存在一定局限性,仍需高质量临床研究进行进一步证实。

关键词: 腹膜透析, 急性肾损伤, 危重症

Abstract: 【Abstract】Peritoneal dialysis (PD) is a useful method of renal replacement therapy for acute kidney injury (AKI). Flexible catheter for PD access is the gold standard in this situation. At present, the best catheterization method for PD in AKI patients is unavailable. The lowest weekly Kt/V of PD can be set at 2.1 for relatively stable AKI patients and at 3.5 for critically ill patients. Automated peritoneal dialysis (APD) is more labor- saving than manual PD in the treatment of AKI with high volume peritoneal dialysis (HVPD). However, there remain some limitations for PD in treatment of AKI. High quality clinical studies are required for further confirmation.

Key words: Peritoneal dialysis, Acute kidney injury, Critical illness