中国血液净化

中国血液净化 ›› 2021, Vol. 20 ›› Issue (08): 555-558.doi: 10.3969/j.issn.1671-4091.2021.08.012

• 综述 • 上一篇    下一篇

体外器官支持治疗的进展

王敏敏   

  1. 1百特(中国)投资有限公司医学部
  • 收稿日期:2021-04-02 修回日期:2021-06-01 出版日期:2021-08-21 发布日期:2021-08-05
  • 通讯作者: 王敏敏 mmwang@outlook.com E-mail:mmwang@outlook.com

The development of extracorporeal organ support therapy

  1. 1Medical Department, Baxter Healthcare, Shanghai 200031, China
  • Received:2021-04-02 Revised:2021-06-01 Online:2021-08-21 Published:2021-08-05

PDF

803

摘要： 【摘要】多器官衰竭是重症患者最常见的死亡原因之一，体外器官支持可用于支持器官衰竭。肾脏替代，体外膜氧合，体外二氧化碳(CO2)清除和人工肝支持都被用于特定的器官支持系统，由于器官之间的器官交互作用，多器官支持疗法(multiple organ support therapy, MOST)可为不同的衰竭器官提供联合支持，将肾脏替代，白蛋白透析，体外CO2清除和细胞因子清除等技术的模块化组合是第一步，集成式多器官支持平台是未来发展方向。

关键词: 体外器官支持, 肾脏替代治疗, 白蛋白透析, 血液吸附, 体外CO2清除

Abstract: 【Abstract】Multiorgan failure is one of the most frequent causes for death in critically ill patients. Extracorporeal organ supports are now available for the treatment of organ failures. For example, renal replacement therapy, extracorporeal membrane oxygenation, extracorporeal CO2 removal (ECCO2R) and extracorporeal liver support have been used as the stand-alone single organ support systems. Considering multiple“crosstalk” interactions between organs, multiple organ support therapy(MOST) can cooperatively support the patients with different organ failures. Combined modules consisting of prEexisted technologies such as renal replacement, albumin-dialysis, ECCO2R and cytokine elimination are the first step to be considered. Integrated platform
with the capacity to support multiple organs is expected to be developed.

Key words: Extracorporeal organ support, Renal replacement therapy, Albumin dialysis, Hemadsorption, Extracorporeal CO2 removal

中图分类号: