中国血液净化

中国血液净化 ›› 2023, Vol. 22 ›› Issue (1): 68-72.doi: 10.3969/j.issn.1671-4091.2023.01.016

• 护理研究 • 上一篇    下一篇

5E康复模式对维持性血液透析患者微炎症状态及生活质量的影响

郑梦蕾   舒亮辉   

  1. 214044 无锡，1苏州大学附属无锡市第九人民医院肾内科
  • 收稿日期:2022-06-20 修回日期:2022-10-17 出版日期:2023-01-12 发布日期:2023-01-12
  • 通讯作者: 舒亮辉 E-mail:dr_shulh@163.com
  • 基金资助:
    无锡市卫健委青年科研项目(Q201753)

Effect of 5E rehabilitation model(encouragement、education、exercise、employment、evaluation)on micro-inflammatory state and quality of life among patients undergoing hemodialysis

ZHENG Meng-lei,   SHU Liang-hui   

  1. Department of Nephrology, Wuxi Nineth People，s Hospital Affiliated to Soochow University, Wuxi 214044, China
  • Received:2022-06-20 Revised:2022-10-17 Online:2023-01-12 Published:2023-01-12
  • Contact: 214044 无锡，1苏州大学附属无锡市第九人民医院肾内科 E-mail:dr_shulh@163.com

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摘要： 目的  观察5E康复模式对维持性血液透析(maintenance hemodialysis,MHD)患者微炎症状态及生活质量的影响。 方法  选择2020年1月～2021年12月在苏州大学附属无锡市第九人民医院血液净化中心MHD患者120例。按照随机数表法分为对照组及观察组，各60例。对照组采用常规护理干预，观察组在常规护理基础上联合5E康复模式干预。比较2组患者微炎症指标[血清超敏C反应蛋白(hs-CRP)、肿瘤坏死因子α(TNF-α)及白细胞介素-6(IL-6)]、营养不良-炎症评分(malnutrition inflammation score,MIS)及健康状况调查表(36-item short form health survey,SF-36)各维度项目的变化。 结果  干预6个月后，观察组hs-CRP、TNF-α、IL-6水平及MIS评分均低于对照组(t=2.300、4.959、2.649、2.298,P =0.023、＜0.001、0.009、0.024)。干预后观察组患者SF-36量表生理机能、生理职能、一般健康状况、躯体疼痛、精力、情感职能、社会功能维度得分均高于对照组(t=-2.527、-3.220、-2.963、0.002、-5.963、4.959、-4.177,P=0.013、0.002、0.004、0.001、＜0.001、＜0.001、＜0.001)。 结论  5E康复模式能够有效改善MHD患者的微炎症状态及营养状态，并提高患者的生活质量。

关键词: 5E康复模式, 维持性血液透析, 微炎症状态, 健康状况调查表, 临床疗效

Abstract: Objective  To investigate the effect of 5E rehabilitation model on micro-inflammatory state and quality of life among patients undergoing hemodialysis.  Methods  A total of 120 maintenance hemodialysis patients treated in the Blood Purification Center of Wuxi 9th Hospital Affiliated to Soochow University were selected and randomly divided into control group (n=60) and observation group (n=60). Patients in the control group were conducted conventional nursing, while the observation group conducted 5E rehabilitation model on the basis of conventional nursing. After 6 months of intervention, the level of hs-CRP、TNF-α、IL-6 and malnutrition inflammation score and 36-item short form health survey scores were compared between two groups.   Results  After 6 months of intervention, the levels of hs-CRP、TNF-α、IL-6 and malnutrition-inflammation scores in the observation group were lower than these in the control group respectively(t=2.300,4.959,2.649,2.298,P=0.023,＜0.001,0.009, 0.024). There was no significant difference in the score of SF-36 dimension item of mental health between the observation group and the control group(t=-1.877,P=0.063). Item scores of other dimensions in the observation group were higher than these in the control group (t=-2.527, -3.220,-2.963,0.002,-5.963,4.959,-4.177,P=0.013,0.002,0.004,0.001,＜0.001).  Conclusion  5E rehabilitation model may effectively improve the micro-inflammatory state, nutritional status and quality of life among MHD patients.

Key words: 5E rehabilitation model, Maintenance hemodialysis, Micro-inflammatory state, 36-item short form health survey, Clinical therapeutic effect

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