中国血液净化

中国血液净化 ›› 2023, Vol. 22 ›› Issue (09): 658-662.doi: 10.3969/j.issn.1671-4091.2023.09.005

• 临床研究 • 上一篇    下一篇

增量血液透析对透析充分性影响的Meta分析

王 顺  张 丽  杨文君  王诗涵  买尔孜亚•吾斯曼  吾尔古丽•阿卜杜喀迪尔   陆 晨   

  1. 830054 乌鲁木齐，1新疆医科大学第一附属医院肾脏疾病中心
  • 收稿日期:2023-04-10 修回日期:2023-06-27 出版日期:2023-09-12 发布日期:2023-09-12
  • 通讯作者: 陆晨 E-mail:luchen706@163.com
  • 基金资助:
    中央引导地方科技发展专项资金项目(ZYYD2022C18)

The effect of incremental hemodialysis on dialysis adequacy: a meta-analysis

WANG Shun, ZHANG Li, YANG Wen-jun, WANG Shi-han, MAIERZIYA Usman, WUERGULI Abdukadir, LU Chen   

  1. Department of Nephrology, Kidney Disease Center, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China
  • Received:2023-04-10 Revised:2023-06-27 Online:2023-09-12 Published:2023-09-12
  • Contact: 830054 乌鲁木齐，1新疆医科大学第一附属医院肾脏疾病中心 E-mail:luchen706@163.com

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摘要： 目的  通过Meta分析探讨增量血液透析对透析充分性及患者预后的影响。 方法 在PubMed、Web of Science、Cochrane library、中国知网(CNKI)、万方数据库(WanFang)、维普数据库(VIP)等数据库中全面检索文献，采用Review Manager 5.4软件进行Meta分析。 结果  依据纳入和排除标准最终纳入文献6篇。常规血液透析与增量血液透析的患者透析充分性之间差异无统计学意义(MD=-0.19，95% CI：-0.62～0.24，Z=0.88,P=0.38)；死亡率之间差异无统计学意义(MD=0.48，95% CI：0.06～4.24,Z=0.65，P=0.51)。 结论  与常规血液透析相比，增量血液透析患者透析充分性无降低，死亡率无升高。对有残余肾功能的血液透析患者，增量血液透析是一种较为理想的透析模式。

关键词: 增量透析, 血液透析, 透析充分性, 死亡率

Abstract: Objective  To investigate the effect of incremental hemodialysis on dialysis adequacy and patient prognosis through meta-analysis.  Methods  A comprehensive literature search was conducted in PubMed, Web of Science, Cochrane library, China National Knowledge Infrastructure (CNKI), Wanfang database (WanFang), and VIP database (VIP). Meta-analysis was undertaken using the software Review Manager version 5.4.  Results  Six articles were finally included according to the inclusion and exclusion criteria. There were no statistical differences in dialysis adequacy (MD=-0.19, 95% C1：-0.62～0.24, Z=0.88, P=0.38) and mortality rate (MD=0.48, 95% C1： 0.06～4.24, Z=0.65, P=0.51) between conventional hemodialysis and incremental hemodialysis. Conclusions  Incremental hemodialysis had no influences on dialysis adequacy and mortality, as compared with those of conventional hemodialysis. Therefore, incremental hemodialysis is an ideal mode of hemodialysis for patients with residual renal function.

Key words: Incremental dialysis, Hemodialysis, Dialysis adequacy, Mortality

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