中国血液净化

中国血液净化 ›› 2025, Vol. 24 ›› Issue (11): 938-941.doi: 10.3969/j.issn.1671-4091.2025.11.013

• 综述 • 上一篇    下一篇

透析血流速度对透析患者预后影响的研究进展

张越明    张周沧   

  1. 102206 北京，1北京大学国际医院肾内科
  • 收稿日期:2025-04-08 修回日期:2025-06-14 出版日期:2025-11-12 发布日期:2025-11-12
  • 通讯作者: 张周沧 E-mail:andyzhoucang@126.com

Recent progresses in impact of dialysis blood flow rate on prognosis in hemodialysis patients

ZHANG Yue-ming  ZHANG Zhou-cang   

  1. Department of Nephrology, Peking University International Hospital, Beijing 102206, China
  • Received:2025-04-08 Revised:2025-06-14 Online:2025-11-12 Published:2025-11-12
  • Contact: 102206 北京，1北京大学国际医院肾内科 E-mail:andyzhoucang@126.com

摘要： 提高透析血流速度(dialysis blood flow rate,DBFR)通过增加透析器的血液量，提高溶质清除率，是确保血液透析治疗充分性的关键因素。充分的透析对于降低维持性血液透析(maintenance hemodialysis,MHD)患者的发病率和死亡率至关重要。鉴于各国透析实践模式的不同，为MHD患者制定适合的DBFR仍然存在争议。本文综述了DBFR的现状、其与MHD患者临床预后的关系及潜在机制。

关键词: 透析血流速度, 血液透析, 预后, 心血管, 动静脉内瘘

Abstract: Increasing the dialysis blood flow rate enhances the blood volume through dialyzer and thereby improves solute clearance, which is a critical factor in ensuring adequate hemodialysis. Adequate dialysis is essential for reducing morbidity and mortality in maintenance hemodialysis (MHD) patients. However, data from Dialysis Outcomes and Practice Patterns Study (DOPPS) indicate significant international variations in dialysis blood flow rate. Due to the differences in dialysis practice across countries, establishing an optimal dialysis blood flow rate for MHD patients remains controversial. This review examines the current status of dialysis blood flow rate, their relationship with clinical outcomes in MHD patients, and the underlying mechanisms.

Key words: Dialysis blood flow rate, Hemodialysis, Prognosis, Cardiovascular, Arteriovenous fistula

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