中国血液净化

中国血液净化 ›› 2026, Vol. 25 ›› Issue (02): 133-137.doi: 10.3969/j.issn.1671-4091.2026.02.010

• 临床研究 • 上一篇    下一篇

腹膜透析患者容量负荷管理变化轨迹及其与体力活动的关系

黄薇薇   周婷婷   

  1. 210000 南京，1 南京大学医学院附属金陵医院(东部战区总医院)肾脏病科
  • 收稿日期:2025-05-27 修回日期:2025-12-11 出版日期:2026-02-12 发布日期:2026-02-02
  • 通讯作者: 周婷婷 E-mail:382881190@qq.com
  • 基金资助:
    江苏省实施“终末期肾病患者腹膜透析治疗可及性及其基层管理模式探索项目”(YYS2016001)

The changing trajectory of volume load management and its relationship with physical activity in peritoneal dialysis patients

HUANG Wei-wei1 , ZHOU Ting-ting   

  1. 1Department of Nephrology, Jinling Hospital, Nanjing University Medical School, Nanjing 210000, China
  • Received:2025-05-27 Revised:2025-12-11 Online:2026-02-12 Published:2026-02-02
  • Contact: 210000 南京，1南京大学医学院附属金陵医院(东部战区总医院)肾脏病科 E-mail:382881190@qq.com

摘要： 目的 探索腹膜透析患者容量负荷管理变化轨迹，并探讨不同轨迹与体力活动的关系。 方 法 便利抽样法选取腹膜透析患者，分别在初始透析1周内(T1)、规律透析1个月(T2)、3个月(T3)和6个 月(T4)对其进行问卷调查。 结果 共纳入155例患者，在T4时间点失访8例，共回收有效问卷147份。共 识别3条容量负荷管理轨迹，即低水平上升组(C1)(n=50)、中水平上升组(C2)(n=56)、低-中水平波动组 (C3)(n=41)。不同轨迹类别患者在文化程度(χ2 =13.570，P=0.035)、糖尿病肾病(χ2 =11.640，P=0.003)、期 间并发腹膜炎(χ2 =18.677，P＜0.001)及低蛋白血症(χ2 =6.947，P=0.031)方面比较差异有统计学意义。腹 膜透析 6 个月(T1～T4)各组患者体力活动得分均呈上升趋势(C1：F=109.134，P＜0.001；C2：F=46.537， P＜0.001；C3：F=33.361，P＜0.001)；T1～T4 阶 段，3 组 间 体 力 活 动 得 分 存 在 统 计 学 差 异(T1：F=5.364， P=0.005；T2：F=9.015，P＜0.01；T3：F=27.156，P＜0.001；T4：F=40.333，P＜0.001)。 结论 文化程度、糖 尿病肾病、期间并发腹膜炎及低蛋白血症对腹膜透析患者容量负荷管理变化轨迹有影响，不同时间阶段 的容量负荷管理均对患者的体力活动有影响。

关键词: 腹膜透析, 容量负荷, 容量管理, 体力活动

Abstract: Objective To explore the trajectory change of volume load management, and to discuss the correlation between different trajectories and physical activity in peritoneal dialysis (PD) patients. Methods A total of 155 patients undergoing PD were selected by convenience sampling. A questionnaire was used to conduct surveys on them within one week of the initial dialysis (T1), and after regular dialysis for one month (T2), 3 months (T3), and 6 months (T4). Result Three volume load management trajectories were identified, namely the low-level upward group (C1, n=50), the medium-level upward group (C2, n=56), and the low-tomedium-level fluctuation group (C3, n=41). There were significant differences among the 3 trajectory categories in terms of educational level (χ2 =13.570, P=0.035), diabetic nephropathy (χ2 =11.640, P=0.003), concurrent peritonitis during the period (χ2 =18.677, P＜0.001), and hypoproteinemia (χ2 =6.947, P=0.031). Within the initial 6 months of PD (T1-T4), physical activity scores of the patients showed an upward trend in every group (C1: F=109.134, P＜0.001; C2: F=46.537, P＜0.001; C3: F=33.361, P＜0.001); during T1-T4 stages, there were significant differences in distribution of physical activity scores among the three groups (T1: F= 5.364, P=0.005; T2: F=9.015, P＜0.01; T3: F=27.156, P＜0.001; T4: F=40.333, P＜0.001). Conclusion Educational level, diabetic nephropathy, concurrent peritonitis and hypoproteinemia have impacts on trajectory change of volume load management in PD patients. Moreover, volume load management at different stages have impacts on physical activity of the patients.

Key words: Peritoneal dialysis, Capacity load, Capacity management, Physical activity

中图分类号: