【摘要】目的 了解腹膜透析患者腹膜转运类型与炎症反应、营养不良的相关关系。方法 对46例腹膜透析患者行腹膜平衡试验（PET），根据PET结果将腹膜转运功能分为高转运（H）、高于平均(HA)、低于平均(LA)和低转运(L)四型。检查血TNF-α、IL-6以及白蛋白水平，并用主观整体评估（SGA）法评估患者的营养状态。结果 TNF-α水平高转运与低转运相比，差异有显著性(P<0.05)；而白蛋白高转运与低转运相比，差异也有显著性(P<0.05)；IL-6则无显著性差异。根据SGA标准，H营养不良的发生率较L显著增高 (P<0.05)。结论 腹膜通透性高的患者其炎症反应和营养不良的发生率高，说明高通透性的腹膜转运类型是造成炎症反应、营养不良的主要原因。

【Abstract】Objective To investigate the relationship between increased peritoneal transport rate and inflammation, malnutrition. Methods 46 CAPD patients were included in the study. The peritoneal transport function was divided into high transportation, high average, low average and low transportation according to the result of PET. Plasma TNF-α、IL-6 and albumin were tested by biochemical instruments. Their nutritional status were also measured using subjective global assessment (SGA). Results There were 5 cases of low transportation(L), 13 cases of low average (LA), 20 cases of high average(HA) and 8 cases of high transportation type(H) according to PET results. The TNF-α was significantly higher and albumin level was significantly lower in high transport rate patients(P<0.05), while IL-6 was no significantly difference. According to SGA, there was much more malnutrition in high transport rate patients than that in low transport rate(P<0.05). conclusion The incidence of inflammation and malnutrition was higher in the high transport patients. It is suggested high transport rate may lead to inflammation, malnutrition.