中国血液净化

›› 2002, Vol. 1 ›› Issue (11): 14-16.

• 论著 • 上一篇    下一篇

腹水浓缩滤菌经血回输术治疗血吸虫性肝硬化腹腔感染患者临床研究

黄建荣 李兰娟 陈亚岗 徐小微 陈月美 杨 芊   

  1. 310003 杭州，浙江大学医学院附属第一医院
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2002-11-19 发布日期:2002-11-19

  • Received:1900-01-01 Revised:1900-01-01 Online:2002-11-19 Published:2002-11-19

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摘要： 【摘要】目的 探索腹水浓缩滤菌经血回输术治疗血吸虫性肝硬化腹腔感染患者的疗效及机理。方法 对5例血吸虫性肝硬化腹腔感染患者进行8次腹水浓缩滤菌经血回输术治疗，治疗前后检测血肝功能、电解质和腹水中蛋白质、细胞数、内毒素变化，并密切观察临床症状和体征变化。结果 治疗后，患者腹胀、纳差明显好转，腹围、体温明显下降，肝功能中血白球蛋白比例由治疗前的(1.15±0.37)g/dl升至(1.31±0.4)g/dl，血白蛋白由(3.1±0.7)g/dl升至(3.5±1.2)g/dl，低钠、低钾血症得到了纠正，回输入血的腹水中蛋白含量明显增高，细胞数下降，内毒素恢复正常，细菌消失。结论 腹水浓缩滤菌经血回输术治疗血吸虫性肝硬化腹腔感染患者疗效可靠，副作用小，值得进一步研究。

关键词: 肝硬化, 腹水, 腹腔感染, 腹水回输

Abstract:

【Abstract】Objective To study the effects and mechanism of ABR to treat patients with peritonitis of Schistosoma cirrhosis. Methods 5 cases of peritonitis of Schistosoma cirrhosis were treated with ABR for 8 times in our hospital. The changes of liver functions, electrolytes, clinical symptoms and signs of these patients were carefully observed before and after each treatment. The concentrations of protein, cells and endotoxin of ascitic fluid were also elevated each time. Results The clinical symptoms such as abdominal distension, lost of appetite were improved obviously. The abdomen circurference and body temperature of these patients were decreased. The blood ration of albumin and globulin of liver function increased from (1.15±0.37)g/dl to (1.31 ±0.4)g/dl, as well as the albumin concentration increased from (3.1±0.7)g/dl to (3.5±1.2)g/dl. The situations of kaliopenia, hyponatremia were also improved. The re-transfusion ascites contained increased protein concentration, decreased cell member, normal endotoxin and no bacteria. Conclusion ABR is an effective method to treat refractory ascites and has slight side effect.

Key words: Ascites, Peritonitis, Asciticre-transfusion