中国血液净化

›› 2002, Vol. 1 ›› Issue (7): 26-28.

• 论著 • 上一篇    下一篇

慢性肾功能衰竭患者血液透析前后心脏结构及功能的变化

张立权 张 英   

  1. 655000 曲靖，云南省曲靖市第一人民医院肾内科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2002-07-19 发布日期:2002-07-19

  • Received:1900-01-01 Revised:1900-01-01 Online:2002-07-19 Published:2002-07-19

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摘要： 【摘要】目的 了解血液透析患者左心室结构和功能在透析前后的变化及临床意义。方法 采用超声心动图仪观测慢性肾功能衰竭患者血液透析6个月前后左心室结构及功能的变化，设两组，即健康对照组30例患者，肾功能衰竭组28例患者。结果 慢性肾功能衰竭患者透析6个月后,血压增高，室间隔厚度增加，左室心肌重量增加，舒张期功能下降，与透析前相比较有显著差异（P<0.01）。左室后壁增厚但与透析前比较无显著差异，（P>0.05）。结论 慢性肾功能衰竭患者经碳酸氢盐长期透析后，左心室肥厚，左心室舒张功能下降，提示左心室重塑，舒张功能下降是血液透析的常见并发症。

关键词: 血液透析, 心肌肥大, 心功能

Abstract: 【Abstract】Objective To investigate the changes and clinical significance of the structure and function of heart before and after hemodialysis in patients with chronic renal failure (CRF). Methods Twenty eight patients with CRF were included in the study. Thirty healthy volunteers were chosen as normal control. The left ventricle structure and cardiac function were assessed with echocardiograph before and six months after emodialysis treatment. Results Six months after dialysis, blood pressure was significantly elevated, interventricular septum thickness and left ventricle myocardium weight increased significantly (P<0.01) while left ventricle diastolic function decreased (P<0.01). No significant change was observed in left ventricle posterior wall thickness before and after hemodialysis(P>0.05). Conclusion The patients with CRF were suffered from left ventricle myocardium hypertrophy and left ventricle diastolic dysfunction after long term bicarbonate dialysis. It was suggested that left ventricle remodeling and diastolic dysfunction were common complications of dialysis treatment.

Key words: Myocardium hypertrophy, Ventricular function 