【摘要】目的 探讨钠超滤曲线模式透析（PHD）对尿毒症患者透析时的血容量维持作用。方法 选择10例常规血液透析患者，每例患者常规血液透析模式（CHD）与钠及超滤曲线透析模式交替进行各5次，观察两种透析模式下患者血容量的变化，同时观察患者血球压积、血压、透析后血浆钠浓度及透析时症状发生率的变化。结果 钠及超滤曲线模式透析较普通透析血容量下降明显减少(P<0.05)，红细胞压积增加明显减少（P<0.05），血压下降幅度明显减少（P<0.05），透析后血浆钠水平无明显变化(P>0.05)，透析中及透析后患者出汗、肌肉痉挛症状明显减少（P<0.05）。结论 钠及超滤曲线模式透析防止了透析患者血容量的明显减少，减少了透析并发症，增加了患者透析耐受性，是一种行之有效的方法。

【Abstract】Objective The author wants to investigate on blood volume preservation for patients suffering from uremia with sodium profile combined with ultrafiltration profile. Methods 10 patients suffering from uremia with conventional hemodialysis were chosen randomly.Every patient underwent with conventional hemodialysis treatment and sodium profile combined with ultrafiltration profile treatmemt 5 times alternatively.And then observed the blood volume changes,hematacrit changes and the blood pressure changes of patients under the two moods of treatments.And also after hemodialysis observed the sodium level in blood plasma and clinical symptoms during treatments. Results The blood volume decrease of sodium profile combined with ultrafiltratiom profile evidently reduced than conventional profile(P<0.05), the hematacrit increase evidently reduced(P<0.05), the blood pressure falling range evidently reduced(P<0.05). Conclution Sodium prlfile combined with ultrafiltration profile provents the blood volume of hemodialysis patiemts evidently reducing, reduces the posibility of profile complications and increases the ability to endure sufferings to patients. The sodium profile combined with ultrafiltration profile is an effective medical treatment.