中国血液净化

›› 2002, Vol. 1 ›› Issue (8): 24-26.

• 论著 • 上一篇    下一篇

On-line 血液透析滤过对老年尿毒症患者的影响

孙延兵 陈秉良 贾 强   

  1. 100053 北京，首都医科大学宣武医院肾内科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2002-08-19 发布日期:2002-08-19

  • Received:1900-01-01 Revised:1900-01-01 Online:2002-08-19 Published:2002-08-19

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摘要： 【摘要】目的 探讨on-line血液透析滤过（HDF－OL）的临床疗效及老年尿毒症患者对治疗的耐受性。方法 15例对常规血液透析（HD）效果不好或耐受性差的老年尿毒症患者，进行了198次HDF-OL治疗，并与行HD治疗时BUN、Scr、iPTH、β2-MG等的清除及临床耐受性进行了对比。结果 HDF-OL对β2-MG及iPTH的清除率显著优于HD，患者对治疗的耐受性明显提高，此外，患者因继发感染的平均住院次数及住院日明显下降。结论 HDF-OL显著提高了透析的效果，减少了HD时高血压、低血压、心律失常、心绞痛、难以纠正的心力衰竭等症状的发生率，提高了老年透析患者对治疗的耐受性，改善了患者的生存质量，为老年尿毒症患者提供了一个安全、高效的治疗模式。

关键词: 血液透析滤过, 血液透析, 老年, 尿毒症, 治疗耐受性

Abstract: 【Abstract】 Objective To investigate the effect of on-line hemodiafiltration (HDF-OL) and the tolerance to treatment in the elderly patients. Methods 198 times of treatments of HDF-OL were performed on 15 elderly patients with hypertension, hypotension, arrhythmia, angina pectoris and refractory heart failure undergoing hemodialysis(HD). Results The clearances of β2-MG and iPTH were significantly improved by HDF-OL than those by HD; the tolerance to treatment of the patients were improved significantly when received HDF-OL; Furthermore, after HDF-OLtreatment, the times and days of admitting to hospital with secondary infections markedly decreased. Conclusion HDF-OL can provide a safe and effective method for the elderly patients with uremia. It will improve the tolerance to treatment of the eldly patients, decrease the incidences of hypertension, hypotension, arrhythmia, angina pectoris and heart failure during treatment, and improve the life quality of elderly patients.

Key words: Hemodialysis, Elderly, Uremia, Tolerance to treatment