中国血液净化

›› 2002, Vol. 1 ›› Issue (9): 23-25.

• 论著 • 上一篇    下一篇

在普通透析机上行血液透析滤过的方法及对老年透析患者的疗效

周再生 叶 晴 陈 小 红 梁 少 媚   

  1. 528403 广东省中山市人民医院血液净化中心
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2002-09-19 发布日期:2002-09-19

  • Received:1900-01-01 Revised:1900-01-01 Online:2002-09-19 Published:2002-09-19

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摘要： 【摘要】目的 探讨一种简单、实用、经济的血液透析滤过置换液的配制方法在普通透析机上行血液透析滤过（HDF）对老年透析患者常见并发症的疗效。方法 治疗组：观察20例老年透析患者行HDF治疗一年治疗过程中低血压、头痛、心律失常、心绞痛、肌痉挛的发生率；对照组：回顾分析20例老年透析患者在此一年前行常规透析时上述并发症的发生率。并计算两组透后甲状旁腺素（PTH）下降率、ß2微球蛋白（ ß2-MG）下降率、血清磷的下降率。结果 治疗组上述透析并发症的发生率较对照组明显降低（P<0.05），PTH下降率、ß2-MG下降率、血清磷的下降率较对照组明显下降（P<0.01）。结论 自配置换液在普通透析机上行血液透析滤过简单、经济，能明显降低老年透析患者相关透析并发症，对中分子物质清除率明显优于常规透析，值得推广应用。

关键词: 血液透析滤过, 置换液, 并发症, 中分子物质

Abstract: 【Abstract】objective To study a feasible and economical method preparing subsititution fluid for hemodiafiltrarion(HDF) on sigle pump hemodialysis machine and the effect in elderly. Methods Observed the morbidity of interdialytic hypotensive, headache, arrhythmia, angina pectoris, muscular cramps and the reduction rate of parathyroid hormone (PTH) and beta2 microglobulin (ß2-MG) and serium phosphate in 20 cases of elderly patients treated with HDF for one year compared to those when they were routinely treated with hemodialysis(HD) one year ago. Results the morbidity of interdialytic hypotensive, headach, arrhythmia, angina pectoris, muscular cramps was significantly lower in HDF than in HD (P<0.05), the reduction rate of PTH and ß2-MG and phosphate was significantly higer in HDF than in HD (P<0.01). Conclusions The method of HDF on sigle pump hemodialysis machine is simple and feasible and economical, significantly reduce the morbidity of interdialytic complications in the elderly, the reduction rate of middle molecule toxins is significantly higer in HDF than in HD.

Key words: Substitution fluid, Complication, Middle molecules