目的 观察连续性肾脏替代疗法（CRRT）治疗慢性肾功能衰竭（CRF）伴心、肺功能衰竭的疗效。方法 18例CRF伴心、肺功能衰竭不能进行常规血液透析与腹膜透析治疗的患者接受CRRT治疗,其中连续性静-静脉血液透析滤过（CVVHDF）10例，连续性静-静脉血液透析（CVVHD）2例，连续性静-静脉血液滤过（CVVH）3例，单纯性超滤（SCUF）3例。结果 均能满意控制水、电解质和酸碱平衡，显著降低尿毒症毒素。本组死亡4例，占23.5%。死亡原因中，CRF同时合并心力衰竭、慢性呼吸衰竭的患者死亡率高达75%。结论 CRRT是CRF患者合并心、肺功能衰竭时不能进行常规血液透析与腹膜透析治疗时的有效方法，且患者耐受性好。

Objective To observe the efficacy of continuous renal replacement therapy(CRRT) in chronic renal failure(CRF) patients with cardic or/and pulmonay failure. Methods 18 CRF with cardic or/and pulmonay failure were evaluated, 10 patients with CVVHDF, 2 patients with CVVHD，3 patients with CVVH and 3 patients with SCUF. Results water, potassium and acid-base balance were maitainted and uremia toxin were reduced obviously in all patients. Conclusion CRRT is effective therapy method for CRF patients with cardic or/and pulmonay failure. 