关键词: 血液透析, 低血压

Abstract: Objective Intradialytic hypotension (IH) is a common complication during dialysis. There are several commonly utilized therapies of IH, however they have not been compared in the same group. The purpose of this study is to investigate the effects of different protective strategies on preventing dialysis hypotension. Methods A single-blind study was undertaken in 12 hemodialysis patients with a prior history of IH. First each patient took for standard dialysis (dialysate sodium 140mmol/L). Then each patient was subjected to take one week each of the four test protocols for.The specific protocols were as follows: high sodium dialysate in which the dialysate sodium was 150mmol/L during first four hours,and followed by a dialysate sodium of 135mmol/L during the last 30 minutes; simple isolated ultrafiltration +HD, in which 1/2 hour of isolated ultrafiltration followed by four hours of isovolemic dialysis; cool temperature dialysis, in which the dialysate was cooled to 34.5℃～35.5℃; and cool dialysate+high sodium dialysis. Results There were significantly fewer hypotensive episodes of follow treatments as the high sodium dialysis, cool dialysis and cool dialysis+high sodium dialysis compared with the standard protocol. Ultrafiltration followed by dialysis could not decrease the episodes of hypotension. Conclusion This study suggests that cool temperature dialysis and high sodium dialysis are of benefit to patients with IH, and for those whose weight loss are more than 2.8kg, ultrafiltration followed by dialysis could not diminish the episodes of hypotension. 

Key words: Hypotension 