目的 前瞻性观察增加透析剂量对长期持续性非卧床腹膜透析（CAPD）患者的营养及透析充分性的影响。方法 36例CAPD患者，均常规行8升/日腹膜透析，其中13例夜间留腹2升，增加腹膜透析剂量为10升/日，随访三个月，评价其营养及透析充分性。结果 13例增加透析剂量组TKt/v和TCcr均显著升高（P<0.05），净超滤亦增加（P<0.05），血浆白蛋白水平虽有下降，但未达到统计学意义。结论 增加腹膜透析剂量能显著提高 TKt/v和TCcr，使透析更为充分，且增加超滤量，对腹膜透析患者的长期存活有意义，且对其营养状态短期内无影响。

Objective To study the effect of increasing dialysis volume on nutritional status and peritoneal dialysis adequacy of continuous ambulatory peritoneal dialysis patients. Methods Thirty-six CAPD patients who took conventional 8-L dialysafe perday were investigated, in which 13 patients had one additional 2-L exchange during the night (10-L group). Dialysis adequcy parameters (TKt/v, TCcr), net ultrafiltration (nUF) and nutritional status (serum albumin) were measured at 0 and 3 months. Results There were significant increases in TKt/v, TCcr and nUF in 10-L group after 3 months ( P<0.05). The serum albumin level were slightly decreased ( P>0.05). Conclusion Increasing dialysis volume may effectively increase TKt/v, TCcr and nUF in CAPD patients, but may not affect nutritional status during short period.