目的 在超滤量不变的条件下分时段适当地调整超滤率，或结合可调节钠血液透析（HD），并与自身常规HD低血压的发生率比较。方法 对32例患者常规HD资料分为老年组与非老年组，按分时段发生的低血压统计分析。并对这些患者调整不同时段超滤率、透析液钠离子浓度进行HD，统计低血压发生率并与患者自身常规HD对照。结果 低血压多发生在3、4小时时段，老年组HD低血压发生率明显高于非老年组。调整不同时段超滤率或结合调节透析液的钠离子浓度，可以减少低血压的发生。结论 血液透析中超滤量过多是发生低血压的关键，在合理超滤量确定后，控制好不同时段的超滤率，适当调节透析液钠离子浓度可以大大降低HD中低血压的发生率。

Objectives Under the condition of constant ultrafiltration volume, to observe the influence of different ultrafiltration rate or it combining with sodium modeling hemodialysis on the frequency of hypotension. Methods Thirty-two patients were divided into the old aged group and the younger aged group. According to the frequency of hypotension during hemodialysis sessions, their regular HD results and HD results after adjusting ultrafiltration rate or it combining with sodium modeling hemodialysis were studied and compared. Result The frequency of hypotension during dialysis was significantly higher in the old aged group compared with that in the younger aged group. Adjusting ultrafiltration rate or it combining with sodium modeling hemodialysis could make the frequency of hypotension became lower. Conclusions The UFV during hemodialysis was a key factor in the occurrence of hypotension. After the proper UFV was determined, the ultrafiltration rate or it combining with sodium modeling hemodialysis were main factors influencing the frequency of hypotension.