目的 研究血液透析患者透析间期体重获得量（IDWG%）与患者营养状况、血压以及生活质 量评分的关系。 方法 连续观察84例维持性血液透析患者12周，记录患者的营养状况（三角肌皮褶厚度、上臂肌肉面积、体重指数）、透析充分性（Kt/V）、标准蛋白分解率（nPCR）和血压变化，进行生活质量SF-36问卷调查。分析IDWG％与上述指标的相关性。并按不同的IDWG％将患者分组，比较组间差异。 结果 IDWG％平均值为(6.8±2.7)%。IDWG％与患者的三角肌皮褶厚度、上臂肌肉面积、体重指数、Kt/V、nPCR 、SF-36体能综合评分、SF-36精神综合评分呈正相关；IDWG%与干体重呈负相关；IDWG%透析前平均动脉压、透析血压下降率无相关性。分组比较表明，IDWG%>8%的患者，透析中血压下降的发生率增大。 结论 在一定范围内，高水平的IDWG％伴随好的营养状况和生活质量，并且对血压影响不大。对透析患者水的限制应该个体化，以提高患者的生活质量。

Objective To determine the relationship between interdialytic weight gain(IDWG％) and the quality of life in hemodialysis patients. Methods We studied 84 stable hemodialysis patients over a 12-week period to track record of anthropometrics measurements, biochemical data and blood pressure changes during hemodialysis. Medical Outcome Study Short Form-36 was administered to evaluate patients' subjective sense of well-being. Results The mean IDWG% was 6.8%±2.7%. A positive correlation were found between IDWG% and triceps skinfold thickness, arm muscle area, body mass index, Kt/V, nPCR, Physical Components Scale and Mental Component Scale. A negative correlation was found between IDWG% and dry weight. There was no correlation between IDWG% and blood pressure. But in group with IDWG% more than 8%, the rate of blood pressure decrease during dialysis was much higher. Conclusions In a certain extension, a greater IDWG% is associated with higher nutritional status and higher self sense of well-being, but not associated with hypertension. IDWG% greater than 8% can cause blood pressure decrease during hemodialysis. 