中国血液净化

›› 2004, Vol. 3 ›› Issue (9): 474-476.

• 论著 • 上一篇    下一篇

早期透析和晚期透析对维持性血液透析患者生存率的影响

张 涛 刘子栋   

  1. 264400 威海，山东省威海市文登中心医院肾内科(张涛)250013 济南，山东省济南市中心医院血液净化中心(刘子栋)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2004-09-12 发布日期:2004-09-12

  • Received:1900-01-01 Revised:1900-01-01 Online:2004-09-12 Published:2004-09-12

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摘要：

目的 探讨维持性血液透析（ MHD）患者早期透析和晚期透析对其累计生存率的影响。方法 从1994年4月～2002年4月在我院行血液透析并要求Kt/V>1.2的患者115例，回顾性分析晚期透析和早期透析与累计生存率的关系。并就其与透析前血压、血清白蛋白(Alb)等因素做比较。结果 115例维持性血液透析患者中平均年龄(52.7±14.3)岁，男女之比为68/47。晚期透析与早期透析的累计生存率比较存在显著性差异（P<0.05）；应用 Independent-sample T检验对其与年龄、血压及血Alb的关系行分层分析。晚期透析组与早期透析组在SBP、DBP、MAP及Alb上均有显著性差异（P<0.01）。结论 本资料显示，晚期透析与早期透析是影响维持性血液透析预后的重要原因，晚期透析预后差可能与其并发症有关，包括低血压、低白蛋白血症等。

关键词: 维持性血液透析, 累计生存率, 早期透析与晚期透析

Abstract:

Objective To observe the effect on cumulative survival-rate of early dialysis and late dialysis in chronic hemodialysis patients. Methods This is a retrospective analysis which included 115 maintenance hemodialysis patients treated between april 1994 and april 2002. Data on the relationship between survival-rate and early dialysis and late dialysis were collected.And analysed other pre-factors consisting hypertension,albumin,et al. Result In this group of patients,the average age they received first hemodialysis session was (52.7±14.3); the male and female ratio was 68/47.The cumulative survival-rate of late dialysis and early dialysis of chronic hemodialysis patients was different significantly（P<0.05）. Independent-sample T test were applied to analyze the relationship between age, hypertension and albumin. The result showed that early dialysis and late dialysis existed significant difference（P<0.01）. Conclusion The outcome of our materials shows that early dialysis and late dialysis are important factors which influenle the surrival rate of hemodialysis patients, the pregnosis of late diagnosis was poor.And late dialysis had relationship with low blood-pressure and hypoalbuminemia.

Key words: Cumulative survival-rate, Early dialysis and late dialysis

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