中国血液净化

›› 2005, Vol. 4 ›› Issue (2): 65-66.

• 论著 • 上一篇    下一篇

老年血液透析患者C－反应蛋白水平与营养状态及贫血的关系

曹礼应 余月明 郭 虹 段 建 王柏青 余开慧 卓红爱
  

  1. 650032 昆明，成都军区昆明总医院肾内科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2005-02-12 发布日期:2005-02-12

  • Received:1900-01-01 Revised:1900-01-01 Online:2005-02-12 Published:2005-02-12

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摘要：

目的 探讨老年持续性血液透析患者C－反应蛋白（CRP）与营养状态及贫血的关系。方法 26例老年及同期27例年轻维持性血液透析患者于透析日空腹采血测定红细胞数（RBC）、血红蛋白（Hb）、红细胞比积（Hct）、转铁蛋白（TF）以及血浆白蛋白（Alb）、血肌酐（SCr）、尿素氮（BUN）和CRP；测定患者肱三头肌皮褶厚度（TSF）、上臂围（AC）、上臂肌围（AMC）等。 结果 老年维持性血液透析患者TSF、AC、AMC、RBC、Hgb、Hct、TF、BUN、SCr、Alb均显著低于年轻组患者，而CRP水平显著高于年轻组患者；老年患者CRP与Hgb、Hct、Alb呈显著负相关（ P<0.01，P<0.01，P<0.05）。 结论 老年血液透析患者营养状况较年轻组患者差，贫血及低蛋白血症严重，贫血、营养不良与炎症反应有一定的关系。

关键词: 血液透析, C－反应蛋白, 贫血, 老年人

Abstract:

Objective To investigate serum C－reactive protein (CRP) level and its correlation with malnutrition,anemia. Methods Twenty-six elderly and 27 young maintenance hemodialysis patients were studied. Blood sample were collected at the day on hemodialysis for the determination of red blood cell（RBC）,hemoglobin (Hgb), hematocrit (Hct), transferrin（TF）, serum albumin(Alb), serum creatinine（SCr）, blood urea nitrogen（BUN）and CRP; and triceps skinfold(TSF), arm circumference（AC）, arm muscle circumference（AMC）were measured. Results The level of TSF、AC、AMC、RBC、Hgb、Hct、TF、BUN、SCr、Alb in elderly maintenance hemodialysis patients was lower than those of young patients;but serum CRP was higher，The serum-CRP is negatively correlated with hemoglobin (Hgb), hematocrit (Hct) and serum albumin（ P<0.01, P<0.01, P<0.05 respetively）in elderly maintenance hemodialysis patients. Conclusion The malnutrition, anemia and hypoproteinemia in elderly maintenance hemodialysis patients are more severe than those of young group, Anemia and malnutrition are correlated with micro-inflammation in elderly maintenance hemodialysis patients.

Key words: C－reactive protein, Anemia, Aged 

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