目的 调查终末期肾病 （ESRD）维持性血液透析（HD）患者的生活质量，分析相关因素。方法 ①用肾脏疾病生活质量简表（KDQOL-SF）对66例ESRD维持性HD患者进行生活质量评分；②分析一般情况、透析情况和各实验室指标对患者生活质量的影响。结果 单因素分析发现不同年龄组、工作状况、文化程度、医疗负担以及内瘘手术次数的患者KDQOL-SF分值差异存在显著性（ P＜0.01，P＜0.01，P＜0.05，P＜0.01，P＜0.01），60岁以上、未就业、文化程度较低、医疗负担较大、内瘘手术次数多的 ESRD维持性HD患者生活质量较差；未发现血红蛋白、血清白蛋白等实验室指标与KDQOL-SF分值之间的相关性。结论 年龄、工作状况、文化程度、医疗负担、内瘘手术次数均对ESRD维持性HD患者生活质量产生影响。

Objective To investigate the Quality of life and it's related factors in the patients with end-stage renal disease (ESRD) undergoing maintenance hemodialysis. Methods Sixty-six patients with ESRD on hemodialysis were assessed by the Kidney Disease Quality of Life short form (KDQOL-SF). The social-family-economic background, dialysis status and biochemistry indicators of these patients were analyzed and their effects on Quality of Life were investigated. Results Univariate analysis demonstrated that older age(≥60), non-working status, low education degree, heavier medical burden or experience more times(≥3) of fistula operation had a significant negative effects on the KDQOL-SF scores (P＜0.01，P＜0.01，P＜0.05，P＜0.01，P＜0.01). We didn't find any significant correlation between the KDQOL-SF score and each biochemistry indicator such as hemoglobin, serum albumin and so on. Conclusions Age, employment status, education degree, medical burden and operation times of internal fistula significantly influence the Quality of Life in these patients. No biochemistry indicator was found to affect the Quality of Life.