96例维持性血液透析患者骨质疏松症患病情况分析

林雅慧; 姜国红; 张东亮; 刘文虎

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中国血液净化 ›› 2007, Vol. 6 ›› Issue (9) : 478-480.

论著

96例维持性血液透析患者骨质疏松症患病情况分析

林雅慧1 姜国红2 张东亮3 刘文虎3

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摘要

目的对维持性血液透析患者(MHD)骨质疏松症患病情况进行横断面研究。方法选择首都医科大学附属北京友谊医院血液净化中心96例维持性血液透析患者按年龄、性别、绝经分组调查身高、体重、骨折、女性月经情况等资料，采用DEXA进行腰椎、股骨骨密度检测。用SSPS软件进行统计学分析。结果骨质疏松症总患病率老年组高于中青年组(P＜0.05)；男女比较差异无明显性。腰椎骨质疏松症患病率女性高于男性(P＜0.05)；中青年与老年比较差异无明显性。股骨骨质疏松症患病率老年组明显高于中青年组(P＜0.01)，绝经组明显高于未绝经组(P＜0.01)；男女比较差异无明显性。结论 MHD患者与健康人群比较骨质疏松症患病率高，性别差异小，发病年龄较早。MHD患者股骨骨质疏松患病情况更严重且骨折危险性大。

Abstract

Objective It was an cross-sectional study about osteoporosis among the maintenance hemodialysis (MHD). Methods Grouping 96 MHD patients by age and sex ,then investigated about their stature/weight/fracture/menstruate et ,detected their bone mineral density (BMD) at the lumbar spine and hip by dual energy X-ray absorptiometry (DEXA).The data were statistically analysized by SPSS software. Results The case rate of osteoporosis in the older significantly more than the middle-age (P＜0.05),but there wasn any obviously difference between the mail and the female. The case rate of the lumbar osteoporosis in the female significantly more than the male (P＜0.05), but there wasn any obviously difference between the older and the middle-age. The case rate of the hip osteoporosis in the older significantly more than the middle-age, such as in the menopause than the nulli-menopause (P＜0.01), but there wasn any obviously difference between the male and the female. Conclusion To compare with the healthy people, the case rate of OP in the MHD was more higher and little sex difference, and age of onset was younger. The case rate of the hip osteoporosis and the chanciness of fracture was also more than the healthy people too.